Long noncoding RNAs and the genetics of cancer
SW Cheetham, F Gruhl, JS Mattick… - British journal of cancer, 2013 - nature.com
Cancer is a disease of aberrant gene expression. While the genetic causes of cancer have
been intensively studied, it is becoming evident that a large proportion of cancer …
been intensively studied, it is becoming evident that a large proportion of cancer …
The long noncoding RNA THRIL regulates TNFα expression through its interaction with hnRNPL
Thousands of large intergenic noncoding RNAs (lincRNAs) have been identified in the
mammalian genome, many of which have important roles in regulating a variety of biological …
mammalian genome, many of which have important roles in regulating a variety of biological …
Gene regulation by the act of long non-coding RNA transcription
Long non-protein-coding RNAs (lncRNAs) are proposed to be the largest transcript class in
the mouse and human transcriptomes. Two important questions are whether all lncRNAs are …
the mouse and human transcriptomes. Two important questions are whether all lncRNAs are …
Long non‐coding RNA s as an epigenetic regulator in human cancers
Y Kondo, K Shinjo, K Katsushima - Cancer science, 2017 - Wiley Online Library
Recent studies have described the important multiple roles of long non‐coding RNA s (lnc
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …
RNA s) during oncogenic transformation. Because the coding genome accounts for a small …
Long non-coding RNAs and cancer: a new frontier of translational research?
Tiling array and novel sequencing technologies have made available the transcription
profile of the entire human genome. However, the extent of transcription and the function of …
profile of the entire human genome. However, the extent of transcription and the function of …
Transposable elements are major contributors to the origin, diversification, and regulation of vertebrate long noncoding RNAs
Advances in vertebrate genomics have uncovered thousands of loci encoding long
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
noncoding RNAs (lncRNAs). While progress has been made in elucidating the regulatory …
[PDF][PDF] Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions
Long noncoding RNAs (lncRNAs) are key regulators of chromatin state, yet the nature and
sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin …
sites of RNA-chromatin interaction are mostly unknown. Here we introduce Chromatin …
[HTML][HTML] Progress toward understanding chromosome silencing by Xist RNA
N Brockdorff, JS Bowness, G Wei - Genes & development, 2020 - genesdev.cshlp.org
The X inactive-specific transcript (Xist) gene is the master regulator of X chromosome
inactivation in mammals. Xist produces a long noncoding (lnc) RNA that accumulates over …
inactivation in mammals. Xist produces a long noncoding (lnc) RNA that accumulates over …
Molecular mechanisms of action of epigallocatechin gallate in cancer: Recent trends and advancement
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid …
Genome-Wide Analysis Uncovers Regulation of Long Intergenic Noncoding RNAs in Arabidopsis
Long intergenic noncoding RNAs (lincRNAs) transcribed from intergenic regions of yeast
and animal genomes play important roles in key biological processes. Yet, plant lincRNAs …
and animal genomes play important roles in key biological processes. Yet, plant lincRNAs …