Dynamic EMT: a multi‐tool for tumor progression
S Brabletz, H Schuhwerk, T Brabletz… - The EMBO journal, 2021 - embopress.org
The process of epithelial–mesenchymal transition (EMT) is fundamental for embryonic
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
morphogenesis. Cells undergoing it lose epithelial characteristics and integrity, acquire …
Tumor immune microenvironment during epithelial–mesenchymal transition
M Taki, K Abiko, M Ukita, R Murakami, K Yamanoi… - Clinical Cancer …, 2021 - AACR
Epithelial–mesenchymal transition (EMT) has been shown to play a critical role in tumor
development from initiation to metastasis. EMT could be regarded as a continuum, with …
development from initiation to metastasis. EMT could be regarded as a continuum, with …
The role of cancer-associated fibroblasts in cancer invasion and metastasis
PJ Asif, C Longobardi, M Hahne, JP Medema - Cancers, 2021 - mdpi.com
Simple Summary Cancer metastasis is often associated with a dismal prognosis for the
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
patient. It is, therefore, crucial to understand the mechanisms behind the cascade of events …
EMT in cancer
Similar to embryonic development, changes in cell phenotypes defined as an epithelial to
mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process …
mesenchymal transition (EMT) have been shown to play a role in the tumorigenic process …
TGF-β orchestrates fibrogenic and developmental EMTs via the RAS effector RREB1
Epithelial-to-mesenchymal transitions (EMTs) are phenotypic plasticity processes that confer
migratory and invasive properties to epithelial cells during development, wound-healing …
migratory and invasive properties to epithelial cells during development, wound-healing …
EMT, cell plasticity and metastasis
CL Chaffer, BP San Juan, E Lim… - Cancer and Metastasis …, 2016 - Springer
Carcinoma cells that are induced to suppress their epithelial features and upregulate
mesenchymal gene expression programs acquire traits that promote an invasive and …
mesenchymal gene expression programs acquire traits that promote an invasive and …
Epithelial–mesenchymal plasticity: a central regulator of cancer progression
X Ye, RA Weinberg - Trends in cell biology, 2015 - cell.com
The epithelial–mesenchymal transition (EMT) program has emerged as a central driver of
tumor malignancy. Moreover, the recently uncovered link between passage through an EMT …
tumor malignancy. Moreover, the recently uncovered link between passage through an EMT …
EMT/MET plasticity in cancer and Go-or-Grow decisions in quiescence: the two sides of the same coin?
A Akhmetkaliyev, N Alibrahim, D Shafiee, E Tulchinsky - Molecular Cancer, 2023 - Springer
Epithelial mesenchymal transition (EMT) and mesenchymal epithelial transition (MET) are
genetic determinants of cellular plasticity. These programs operate in physiological …
genetic determinants of cellular plasticity. These programs operate in physiological …
Regulation of epithelial-mesenchymal transition through epigenetic and post-translational modifications
SJ Serrano-Gomez, M Maziveyi, SK Alahari - Molecular cancer, 2016 - Springer
The epithelial to mesenchymal transition (EMT) is a biological process in which a non-motile
epithelial cell changes to a mesenchymal phenotype with invasive capacities. This …
epithelial cell changes to a mesenchymal phenotype with invasive capacities. This …
Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-β-induced epithelial-mesenchymal transition and metastasis by controlling TIF1γ in non-small cell lung …
L Wang, X Tong, Z Zhou, S Wang, Z Lei, T Zhang, Z Liu… - Molecular cancer, 2018 - Springer
Background TGF-β promotes tumor invasion and metastasis through inducing epithelial-
mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC). Circular RNAs …
mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC). Circular RNAs …