[HTML][HTML] Enhancing risk assessment in patients with diabetic retinopathy by combining measures of retinal function and structure

MG Brigell, B Chiang, AY Maa… - … Vision Science & …, 2020 - iovs.arvojournals.org
Purpose: To determine whether combining measures of retinal structure and function
predicts need for intervention for diabetic retinopathy (DR) better than either modality alone …

[HTML][HTML] Cone photoreceptor irregularity on adaptive optics scanning laser ophthalmoscopy correlates with severity of diabetic retinopathy and macular edema

J Lammer, SG Prager, MC Cheney… - … & visual science, 2016 - tvst.arvojournals.org
Purpose: To determine whether cone density, spacing, or regularity in eyes with and without
diabetes (DM) as assessed by high-resolution adaptive optics scanning laser …

[HTML][HTML] Dopamine deficiency mediates early rod-driven inner retinal dysfunction in diabetic mice

MK Kim, MH Aung, L Mees, DE Olson… - … & visual science, 2018 - jov.arvojournals.org
Purpose: Electroretinograms (ERGs) are abnormal in diabetic retinas before the appearance
of vascular lesions, providing a possible biomarker for diabetic vision loss. Previously, we …

Association between retinal neuronal degeneration and visual function impairment in type 2 diabetic patients without diabetic retinopathy

TP Zhu, J Ma, YH Li, Z Zhang - Science China Life Sciences, 2015 - Springer
The changes in retinal thickness and visual function in type 2 diabetic patients without
clinical evidence of diabetic retinopathy were evaluated. A total of 141 diabetic subjects …

Visual dysfunction in diabetes

ED Eggers - Annual Review of Vision Science, 2023 - annualreviews.org
Although diabetic retinopathy (DR) is clinically diagnosed as a vascular disease, many
studies find retinal neuronal and visual dysfunction before the onset of vascular DR. This …

The Glenn A. Fry award lecture 2010: Ophthalmic markers of diabetic neuropathy

N Efron - Optometry and Vision Science, 2011 - journals.lww.com
Diabetic peripheral neuropathy (DPN) is a debilitating condition that affects about 50% of
diabetic patients. The symptoms of DPN include numbness, tingling, or pain in the arms and …

Early structural and functional neurovascular changes in the retina in the prediabetic stage

D Ratra, R Nagarajan, D Dalan, N Prakash, K Kuppan… - Eye, 2021 - nature.com
Purpose This study was undertaken to investigate the neurovascular changes in the retina of
prediabetic subjects. Methods Subjects enroled in a prospective study were separated into …

[HTML][HTML] Disorganized retinal lamellar structures in nonperfused areas of diabetic retinopathy

Y Dodo, T Murakami, A Uji, S Yoshitake… - … & visual science, 2015 - arvojournals.org
Purpose.: To investigate morphologic changes on spectral-domain optical coherence
tomography (SD-OCT) images in nonperfused areas (NPAs) in diabetic retinopathy (DR) …

Reduction of Glut1 in the neural retina but not the RPE alleviates polyol accumulation and normalizes early characteristics of diabetic retinopathy

NC Holoman, JJ Aiello, TD Trobenter… - Journal of …, 2021 - Soc Neuroscience
Hyperglycemia is a key determinant for development of diabetic retinopathy (DR).
Inadequate glycemic control exacerbates retinopathy, while normalization of glucose levels …

Multifocal electroretinography in diabetic retinopathy and diabetic macular edema

MA Bearse, GY Ozawa - Current diabetes reports, 2014 - Springer
In this review article, we first present a brief overview of the vascular and neural components
of diabetic retinopathy. Next, the multifocal electroretinogram (mfERG) technique, which can …