[HTML][HTML] Cell and animal models for SARS-CoV-2 research
During the last two years following the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic, development of potent antiviral drugs and vaccines has been a …
(SARS-CoV-2) pandemic, development of potent antiviral drugs and vaccines has been a …
[HTML][HTML] Lung organoids as model to study SARS-CoV-2 infection
L Peng, L Gao, X Wu, Y Fan, M Liu, J Chen, J Song… - Cells, 2022 - mdpi.com
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), has become a global pandemic and has severely affected …
coronavirus 2 (SARS-CoV-2), has become a global pandemic and has severely affected …
[HTML][HTML] Establishment of human distal lung organoids for SARS-CoV-2 infection
T Wang, N Zhang, S Fan, L Zhao, W Song, Y Gong… - Cell Discovery, 2021 - nature.com
Dear Editor, COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) is being a serious pandemic with more than 164 million infections and 3.41 million …
CoV-2) is being a serious pandemic with more than 164 million infections and 3.41 million …
[HTML][HTML] Modifications of lipid pathways restrict SARS-CoV-2 propagation in human induced pluripotent stem cell-derived 3D airway organoids
PH Tsai, JR Sun, Y Chien, MS Chan, W Khor… - Journal of Advanced …, 2024 - Elsevier
Background Modifications of lipid metabolism were closely associated with the
manifestations and prognosis of coronavirus disease of 2019 (COVID-19). Pre-existing …
manifestations and prognosis of coronavirus disease of 2019 (COVID-19). Pre-existing …
[HTML][HTML] Human lung organoids as a model for respiratory virus replication and countermeasure performance in human hosts
CE Edwards, A Tata, RS Baric - Translational Research, 2022 - Elsevier
Human respiratory viruses induce a wide breadth of disease phenotypes and outcomes of
varying severity. Innovative models that recapitulate the human respiratory tract are needed …
varying severity. Innovative models that recapitulate the human respiratory tract are needed …
Recent frontiers in biofabrication for respiratory tissue engineering
Respiratory tissue engineering offers a robust framework for studying cell-cell and host-
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
pathogen interactions in a tissue-like environment and offers a platform for studying lung …
[HTML][HTML] Insights into organoid-based modeling of COVID-19 pathology
Since December 2019, various types of strategies have been applied due to the emergent
need to investigate the biology and pathogenesis of severe acute respiratory syndrome …
need to investigate the biology and pathogenesis of severe acute respiratory syndrome …
Animal hosts and experimental models of SARS-CoV-2 infection
C Parolin, S Virtuoso, M Giovanetti, S Angeletti… - Chemotherapy, 2021 - karger.com
Viruses arise through cross-species transmission and can cause potentially fatal diseases in
humans. This is the case of the severe acute respiratory syndrome coronavirus 2 (SARS …
humans. This is the case of the severe acute respiratory syndrome coronavirus 2 (SARS …
[HTML][HTML] Virus infection variability by single-cell profiling
M Suomalainen, UF Greber - Viruses, 2021 - mdpi.com
Cell-to-cell variability of infection has long been known, yet it has remained one of the least
understood phenomena in infection research. It impacts on disease onset and development …
understood phenomena in infection research. It impacts on disease onset and development …
[HTML][HTML] A trifunctional peptide broadly inhibits SARS-CoV-2 Delta and Omicron variants in hamsters
The emergence of highly transmissible SARS-CoV-2 variants has led to the waves of the
resurgence of COVID-19 cases. Effective antivirals against variants are required. Here we …
resurgence of COVID-19 cases. Effective antivirals against variants are required. Here we …