Emerging and re-emerging zoonotic viral diseases in Southeast Asia: One Health challenge

PM Saba Villarroel, N Gumpangseth… - Frontiers in public …, 2023 - frontiersin.org
The ongoing significant social, environmental, and economic changes in Southeast Asia
(SEA) make the region highly vulnerable to the emergence and re-emergence of zoonotic …

Natural products as Zika antivirals

YD Fong, JJH Chu - Medicinal research reviews, 2022 - Wiley Online Library
Zika virus (ZIKV) is an arbovirus belonging to the flavivirus genus and is transmitted in
Aedes mosquito vectors. Since its discovery in humans in 1952 in Uganda, ZIKV has been …

First comprehensive analysis of Aedes aegypti bionomics during an arbovirus outbreak in west Africa: Dengue in Ouagadougou, Burkina Faso, 2016–2017

A Badolo, A Sombié, F Yaméogo… - PLOS Neglected …, 2022 - journals.plos.org
Background Dengue's emergence in West Africa was typified by the Burkina Faso outbreaks
in 2016 and 2017, the nation's largest to date. In both years, we undertook three-month …

A single amino acid substitution in the capsid protein of Zika virus contributes to a neurovirulent phenotype

GY Song, XY Huang, MJ He, HY Zhou, RT Li… - Nature …, 2023 - nature.com
Increasing evidence shows the African lineage Zika virus (ZIKV) displays a more severe
neurovirulence compared to the Asian ZIKV. However, viral determinants and the underlying …

Zika vector competence data reveals risks of outbreaks: the contribution of the European ZIKAlliance project

T Obadia, G Gutierrez-Bugallo, V Duong… - Nature …, 2022 - nature.com
First identified in 1947, Zika virus took roughly 70 years to cause a pandemic unusually
associated with virus-induced brain damage in newborns. Zika virus is transmitted by …

Neuroinvasiveness of the MR766 strain of Zika virus in IFNAR-/- mice maps to prM residues conserved amongst African genotype viruses

E Nakayama, F Kato, S Tajima, S Ogawa, K Yan… - PLoS …, 2021 - journals.plos.org
Zika virus (ZIKV) strains are classified into the African and Asian genotypes. The higher
virulence of the African MR766 strain, which has been used extensively in ZIKV research, in …

The Epidermal Growth Factor Receptor Is a Relevant Host Factor in the Early Stages of The Zika Virus Life Cycle In Vitro

C Sabino, D Bender, ML Herrlein, E Hildt - Journal of virology, 2021 - Am Soc Microbiol
Zika virus (ZIKV) is a flavivirus that is well known for the epidemic in the Americas in 2015
and 2016 in which microcephaly in newborns and other neurological complications were …

Molecular mechanisms of zika virus pathogenesis: An update

R Bhagat, G Kaur, P Seth - Indian Journal of Medical Research, 2021 - journals.lww.com
Zika virus (ZIKV), member of the family Flaviviridae belonging to genus Flavivirus, is an
arthropod-borne virus. The ZIKV is known to cause severe congenital birth defects in …

NS2B‐NS3 protease inhibitors as promising compounds in the development of antivirals against Zika virus: A systematic review

DAF Nunes, FRS Santos… - Journal of Medical …, 2022 - Wiley Online Library
Zika virus (ZIKV) infections are associated with severe neurological complications and are a
global public health concern. There are no approved vaccines or antiviral drugs to inhibit …

Control of maternal Zika virus infection during pregnancy is associated with lower antibody titers in a macaque model

NP Krabbe, E Razo, HJ Abraham, RV Spanton… - Frontiers in …, 2023 - frontiersin.org
Introduction Zika virus (ZIKV) infection during pregnancy results in a spectrum of birth
defects and neurodevelopmental deficits in prenatally exposed infants, with no clear …