Gene therapy, or the treatment of human disease using genetic material, for inner ear
dysfunction is coming of age. Recent progress in developing gene therapy treatments for …

The surgical implant is an interdisciplinary therapeutic modality that offers unique
advantages in the daily practice of otorhinolaryngology. Some well-known examples include …

Although cochlear implant (CI) technology has allowed for the partial restoration of hearing
over the last few decades, persistent challenges (eg, poor performance in noisy …

Impairment of spiral ganglion neurons (SGNs) of the auditory nerve is a major cause for
hearing loss occurring independently or in addition to sensory hair cell damage …

The fibroblast is one of the ideal target cell candidates for cell-based gene therapy
approaches to promote tissue repair. Gene delivery to fibroblasts by viral transfection has …

Disabling hearing loss affects over 5% of the world's population and impacts the lives of
individuals from all age groups. Within the next three decades, the worldwide incidence of …

The cochlear implant provides auditory cues to profoundly deaf patients by electrically
stimulating the primary auditory neurons (ANs) of the cochlea. However, ANs degenerate in …

Hearing loss is an increasing problem for a substantial number of people and, with an aging
population, the incidence and severity of hearing loss will become more significant over …

A new type of super-spiral structure and instability of spiral waves (in numerical simulation)
are investigated. Before the period-doubling bifurcation of this system, the super-spiral …

Sensorineurale Hörstörungen können mit einem Cochlea-Implantat behandelt werden.
Dazu wird ein Elektrodenträger (ET) vom Chirurgen in die Cochlea inseriert, um dort die …