The link between neuroinflammation and the neurovascular unit in synucleinopathies
The neurovascular unit (NVU) is composed of vascular cells, glial cells, and neurons. As a
fundamental functional module in the central nervous system, the NVU maintains …
fundamental functional module in the central nervous system, the NVU maintains …
[HTML][HTML] Efficacy of repetitive transcranial magnetic stimulation in Parkinson's disease: a systematic review and meta-analysis of randomised controlled trials
W Zhang, B Deng, F Xie, H Zhou, JF Guo, H Jiang… - …, 2022 - thelancet.com
Background Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive form of
brain stimulation that positively regulates the motor and non-motor symptoms of Parkinson's …
brain stimulation that positively regulates the motor and non-motor symptoms of Parkinson's …
Inflammasomes in neurological disorders—mechanisms and therapeutic potential
KA Ravichandran, MT Heneka - Nature Reviews Neurology, 2024 - nature.com
Inflammasomes are molecular scaffolds that are activated by damage-associated and
pathogen-associated molecular patterns and form a key element of innate immune …
pathogen-associated molecular patterns and form a key element of innate immune …
Breakthroughs in nanozyme-inspired application diversity
Q Zhang, L Song, K Zhang - Materials Chemistry Frontiers, 2023 - pubs.rsc.org
The rapid advancement of nanomaterials has promoted the booming of nanozymes capable
of mimicking natural enzymes. As ideal alternatives to natural enzymes, nanozymes are …
of mimicking natural enzymes. As ideal alternatives to natural enzymes, nanozymes are …
[HTML][HTML] Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson's disease
HY Yu, T Sun, Z Wang, H Li, D Xu, J An… - Neural Regeneration …, 2023 - journals.lww.com
Use of glucagon-like peptide-1 receptor agonist or dipeptidyl peptidase 4 inhibitor has been
shown to lower the incidence of Parkinson's disease in patients with diabetes mellitus …
shown to lower the incidence of Parkinson's disease in patients with diabetes mellitus …
[HTML][HTML] The role of tyrosine hydroxylase–dopamine pathway in Parkinson's disease pathogenesis
Background Parkinson's disease (PD) is characterized by selective and progressive
dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the …
dopamine (DA) neuron loss in the substantia nigra and other brain regions, with the …
[HTML][HTML] Role of NLRP3 inflammasome in Parkinson's disease and therapeutic considerations
LTN Nguyen, HD Nguyen, YJ Kim… - Journal of …, 2022 - content.iospress.com
Parkinson's disease (PD) is the second most common neurodegenerative disease, with two
main pathological features: misfolded α-synuclein protein accumulation and …
main pathological features: misfolded α-synuclein protein accumulation and …
Dl-3-n-butylphthalide activates Nrf2, inhibits ferritinophagy, and protects MES23. 5 dopaminergic neurons from ferroptosis
Z Ye, C Li, S Liu, H Liang, J Feng, D Lin, Y Chen… - Chemico-biological …, 2023 - Elsevier
Ferroptosis, a newly identified iron-dependent form of cell death, has recently been
implicated in the pathogenesis of Parkinson's disease (PD). Dl-3-n-butylphthalide (NBP) …
implicated in the pathogenesis of Parkinson's disease (PD). Dl-3-n-butylphthalide (NBP) …
[HTML][HTML] Alzheimer's disease and neuroinflammation: will new drugs in clinical trials pave the way to a multi-target therapy?
D Melchiorri, S Merlo, B Micallef, JJ Borg… - Frontiers in …, 2023 - frontiersin.org
Despite extensive research, no disease-modifying therapeutic option, able to prevent, cure
or halt the progression of Alzheimer's disease [AD], is currently available. AD, a devastating …
or halt the progression of Alzheimer's disease [AD], is currently available. AD, a devastating …
[HTML][HTML] Role of Exosomes in the Pathogenesis and Theranostic of Alzheimer's Disease and Parkinson's Disease
A He, M Wang, X Li, H Chen, K Lim, L Lu… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) and Parkinson's disease (PD) are the most common
neurodegenerative diseases (NDDs) threatening the lives of millions of people worldwide …
neurodegenerative diseases (NDDs) threatening the lives of millions of people worldwide …