Nanomedicines for cancer therapy: state-of-the-art and limitations to pre-clinical studies that hinder future developments

CM Dawidczyk, LM Russell, PC Searson - Frontiers in chemistry, 2014 - frontiersin.org
The ability to efficiently deliver a drug or gene to a tumor site is dependent on a wide range
of factors including circulation time, interactions with the mononuclear phagocyte system …

A review on pH and temperature responsive gels and other less explored drug delivery systems

PK Bolla, VA Rodriguez, RS Kalhapure, CS Kolli… - Journal of Drug Delivery …, 2018 - Elsevier
Any imbalance in body's pH or temperature may alter immune response and lead to
conditions such as autoimmune disorders, infectious diseases, cancer, and diabetes. Dual …

Updated but not outdated “Gliadin”: A plant protein in advanced pharmaceutical nanotechnologies

MM Mehanna, AT Mneimneh - International Journal of Pharmaceutics, 2020 - Elsevier
For many years, natural products have been considered as the backbone of medical
therapy. Recently, different extracted active moieties of these botanical plants were …

Zein-casein-lysine multicomposite nanoparticles are effective in modulate the intestinal permeability of ferulic acid

G Heep, A Almeida, R Marcano, D Vieira… - International journal of …, 2019 - Elsevier
The objective of this study was to develop zein-casein-lysine nanoparticles to modulate the
intestinal permeability of ferulic acid (FA), a bioactive compound with proven antioxidant …

Nanomaterials as Microglia Modulators in the Treatment of Central Nervous System Disorders

M Battaglini, A Marino, M Montorsi… - Advanced …, 2024 - Wiley Online Library
Microglia play a pivotal role in the central nervous system (CNS) homeostasis, acting as
housekeepers and defenders of the surrounding environment. These cells can elicit their …

Cereal protein-based nanoparticles as agents stabilizing air–water and oil–water interfaces in food systems

AGB Wouters, JA Delcour - Current Opinion in Food Science, 2019 - Elsevier
Highlights•Cereal proteins are a promising material to produce nanoparticles (NPs).•Such
NPs can be used to stabilize air–water or oil–water interfaces in food systems.•Studies thus …

Exploring a new jellyfish collagen in the production of microparticles for protein delivery

MT Calejo, AJ Almeida… - Journal of …, 2012 - Taylor & Francis
A microparticulate protein delivery system was developed using collagen, from the medusa
Catostylus tagi, as a polymeric matrix. Collagen microparticles (CMPs) were produced by an …

Silk fibroin nanoparticles functionalized with fibronectin for release of vascular endothelial growth factor to enhance angiogenesis

P Zahedi, N Hassani Besheli, M Farokhi… - Journal of Natural …, 2022 - Taylor & Francis
This work aimed at enhancing the angiogenesis in the presence of silk fibroin nanoparticles
functionalized with fibronectin (FN-SF NPs) for controlled release of vascular endothelial …

Layer-by-layer polyelectrolyte coating of alginate microgels for sustained release of sodium benzoate and zosteric acid

Q Wang, BZ Newby - Journal of drug delivery science and technology, 2018 - Elsevier
The potential of sustaining release of very small (Mw< 250 g/mol) hydrophilic drugs up to
several days from layer-by-layer (LbL) polyelectrolyte coated alginate microgels (Alg-Ms) …

A review on potential of proteins as an excipient for developing a nano-carrier delivery system

A Chakraborty, P Dhar - Critical Reviews™ in Therapeutic …, 2017 - dl.begellhouse.com
In neo-age research, nano-materials have emerged as potential tools for the revolution of
diagnostic and therapeutic field because of their nano-scale effects, increased surface area …