Abstract α-Dystroglycanopathy, an autosomal recessive disease, is associated with the
development of a variety of diseases, including muscular dystrophy. In humans, α …

Disuse atrophy is the loss of skeletal muscle mass due to inactivity or lower than 'normal'use.
It is not only a furtive component of the 'modern'sedentary lifestyle but also a part of …

Abstract Duchenne Muscular Dystrophy (DMD) is caused by mutations in the gene coding
for dystrophin and leads to muscle degeneration, wheelchair dependence and death by …

Introduction Duchenne muscular dystrophy (DMD) is a genetic muscle disorder that
manifests during early childhood and is ultimately fatal. Recently approved treatments …

Nexilin (NEXN) plays a crucial role in stabilizing the sarcomeric Z-disk of striated muscle
fibers and, when mutated, leads to dilated cardiomyopathy in humans. Due to its early …

Objective We provide succinct, evidence-based and/or consensus-based best practice
guidance for the cardiac care of children living with Duchenne muscular dystrophy (DMD) as …

The l-arginine/nitric oxide (L-Arg/NO) pathway regulates endothelial function and may play
an important role in the pathogenesis of Duchenne muscular dystrophy (DMD). Yet, this …

Abstract α-Dystroglycanopathies are a group of muscular dystrophies characterized by α-DG
hypoglycosylation and reduced extracellular ligand-binding affinity. Among other genes …

Abstract Myosin Binding Protein-C slow (sMyBP-C), encoded by MYBPC1, comprises a
family of regulatory proteins of skeletal muscles that are phosphorylated by PKA and PKC …

Purpose Timed functional tests have been explored to understand the natural history of
Duchenne muscular dystrophy (DMD) and to establish warning signs of loss of gait. This …