Arylglyoxals in synthesis of heterocyclic compounds

B Eftekhari-Sis, M Zirak, A Akbari - Chemical reviews, 2013 - ACS Publications
Heterocycles are an extraordinarily important class of compounds, making up more than half
of all known organic compounds. Heterocycles are present in a wide variety of drugs, most …

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)

AM Brinker, J Ma, PE Lipsky, I Raskin - Phytochemistry, 2007 - Elsevier
Plants in the genus Tripterygium, such as Tripterygium wilfordii Hook. f., have a long history
of use in traditional Chinese medicine. In recent years there has been considerable interest …

A study of microemulsion systems for transdermal delivery of triptolide

H Chen, X Chang, T Weng, X Zhao, Z Gao… - Journal of controlled …, 2004 - Elsevier
Triptolide possesses immunosuppressive, anti-fertility and anti-cancer activities. Due to its
severe toxicity, microemulsions with controlled, sustained and prolonged delivery of …

The Chinese anti-inflammatory and immunosuppressive herbal remedy Tripterygium wilfordii Hook F

X Tao, PE Lipsky - Rheumatic Disease Clinics of North America, 2000 - Elsevier
Tripterygium wilfordii Hook F (TwHF) is a member of Celastraceae family of perennial vine-
like plants that grow in the wild in southern China along the Yongzhi River and in Fujian …

Triptolide inhibits the growth and metastasis of solid tumors

S Yang, J Chen, Z Guo, XM Xu, L Wang, XF Pei… - Molecular cancer …, 2003 - AACR
Triptolide (TPL), a diterpenoid triepoxide purified from the Chinese herb Tripterygium
wilfordii Hook F, was tested for its antitumor properties in several model systems. In vitro …

Triptolide, a novel immunosuppressive and anti-inflammatory agent purified from a Chinese herb Tripterygium wilfordii Hook F

BJ Chen - Leukemia & lymphoma, 2001 - Taylor & Francis
Triptolide is a diterpenoid triepoxide purified from a Chines herb Tripterygium Wilfordii Hook
F (TWHF). TWHF has been used in traditional Chinese medicine for more than two thousand …

Cytotoxic and antitumor potentialities of aporphinoid alkaloids

C Stevigny, C Bailly… - … Medicinal Chemistry-Anti …, 2005 - ingentaconnect.com
Aporphinoids form an important group of plant secondary metabolites. Some of these
compounds are used for a long time in traditional medicine for the treatment of various …

Longterm effects of triptolide on spermatogenesis, epididymal sperm function, and fertility in male rats

PN Huynh, APS Hikim, C Wang… - Journal of …, 2000 - Wiley Online Library
Prior studies had suggested that triptolide, a diterpene triepoxide isolated from a Chinese
medicinal plant, might be an attractive candidate as a posttesticular male contraceptive …

Investigation on the wound healing activity of oleoresin from Copaifera langsdorffi in rats

LAF Paiva, KM de Alencar Cunha… - … Journal Devoted to …, 2002 - Wiley Online Library
The wound healing activity of oleoresin from Copaifera langsdorffii Desf.(Leguminaceae)
bark was evaluated in rats on experimental wounds. The oleoresin was tested by …

[HTML][HTML] An overview of saturated cyclic ethers: Biological profiles and synthetic strategies

Q Lu, DS Harmalkar, Y Choi, K Lee - Molecules, 2019 - mdpi.com
Saturated oxygen heterocycles are widely found in a broad array of natural products and
other biologically active molecules. In medicinal chemistry, small and medium rings are also …