Idiopathic inflammatory myopathies (IIM), even though sharing common clinical
manifestations, are characterized by diversified molecular pathogenetic mechanisms which …

Introduction Sjögren's Disease, SjD, is a systemic autoimmune disorder characterized by
reduced function of the salivary and lacrimal glands. Patients suffer from dryness, fatigue …

Objectives To investigate the clinical significance of the interferon (IFN) score, especially the
IFN-I score, in patients with anti-melanoma differentiation-associated gene 5 (MDA5) …

The biologic diagnosis of primary Sjögren disease (SjD) mainly relies on anti-Ro60/SSA
antibodies, whereas the significance of anti-Ro52/TRIM21 antibodies currently remains …

Objectives The abnormal DNA damage response is associated with upregulation of the type-
1 interferon (IFN-I) pathway in certain rheumatic diseases. We investigated whether such …

In primary Sjögren's syndrome (pSS) patients, salivary gland (SG) epithelial cells (SGECs)
could be exposed to chronic hyperosmotic stress (HOS), consecutive to their destruction and …

Systemic sclerosis (SSc) is a rare autoimmune connective tissue disorder characterized by
massive fibrosis, vascular damage, and immune imbalance. Advances in rheumatology and …

In the field of complex autoimmune diseases such as systemic lupus erythematosus (SLE),
systems immunology approaches have proven invaluable in translational research settings …

Systemic lupus erythematosus (SLE) is a complex autoimmune disease, which can be
clinically heterogeneous in the same patient over the disease process and has an …

Behçet's Disease (BD) is a rare multisystemic variable vessel vasculitis with a chronic and
relapsing disease course. BD is polygenic, and genome wide association studies in cohorts …