Pressurized metered-dose inhalers (pMDIs) and nebulizers are routinely employed for
aerosol delivery in mechanically ventilated patients. A significant proportion of the aerosol …

The β-agonists have found wide clinical use as racemic mixtures for 20 years, but
information on their pharmacokinetics is not comprehensive. They are well absorbed orally …

There are significant differences in the pharmacokinetic properties of inhaled corticosteroids
currently available for use in treatment of asthma and this can result in differences in …

In selected patients, noninvasive positive pressure ventilation (NIPPV) with a facemask is
now commonly employed as the first choice for providing mechanical ventilation in the …

Study objective: To determine whether β-adrenergic agonist aerosols are more effective in
treating acute bronchospasm if delivered by nasal bilevel positive airway pressure (BiPAP) …

Pressurized metered-dose inhalers (pMDIs) and nebulizers are employed routinely for
aerosol delivery to ventilator-supported patients, but the ventilator circuit and artificial airway …

Pressurized metered-dose inhalers of bronchodilator and corticosteroid aerosols are more
efficient and convenient to use than nebulizers for routine therapy in ventilated patients …

In a double-blind trial we compared the efficacy and safety of inhaled salbutamol (albuterol),
nebulized with oxygen by face mask, and subcutaneous epinephrine in 40 children with …

Background: Aerosol drug delivery during noninvasive ventilation (NIV) is known to be
inefficient due to high depositional losses. To improve drug delivery efficiency, the concept …

We analyzed continuous nebulized terbutaline (CNT) therapy in 19 patients with 27
admissions for severe asthma and impending respiratory failure who failed to respond to our …