Exploiting non-covalent interactions in selective carbohydrate synthesis

CCJ Loh - Nature Reviews Chemistry, 2021 - nature.com
Non-covalent interactions (NCIs) are a vital component of biological bond-forming events,
and have found important applications in multiple branches of chemistry. In recent years, the …

Recent progress in chemical synthesis of bacterial surface glycans

R Li, H Yu, X Chen - Current opinion in chemical biology, 2020 - Elsevier
With the continuing advancement of carbohydrate chemical synthesis, bacterial glycomes
have become increasingly attractive and accessible synthetic targets. Although bacteria also …

Total Synthesis of the Repeating Units of Proteus penneri 26 and Proteus vulgaris TG155 via a Common Disaccharide

A Paul, SS Kulkarni - Organic Letters, 2023 - ACS Publications
Herein, we report the first total synthesis of the trisaccharide and tetrasaccharide repeating
units of P. penneri 26 and P. vulgaris TG155, respectively, having a common disaccharide …

Influence of remote picolinyl and picoloyl stereodirecting groups for the stereoselective glycosylation

A Khanam, P Kumar Mandal - Asian Journal of Organic …, 2021 - Wiley Online Library
Sugar compounds generally consist of several hydroxyl groups, responsible for the
generation of complex oligosaccharides and are discriminated against or manipulated by …

Recent advances in β-L-rhamnosylation

D Rai, SS Kulkarni - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
L-Rhamnose forms the key components of important antigenic oligo-and polysaccharides of
a variety of pathogens. Obtaining 1, 2-cis stereoselectivity in the glycosylation of L …

Reagent-controlled chemo/stereoselective glycosylation of ʟ-fucal to access rare deoxysugars

N Kumar, M Yadav, S Kashyap - Carbohydrate Research, 2024 - Elsevier
Dideoxy sugars constitute an important class of anticancer antibiotics natural products and
serve as essential medicinal tools for carbohydrate-based drug discovery and vaccine …

Total Synthesis of the Repeating Unit of Streptococcus pneumoniae Zwitterionic Polysaccharide Sp1

A Ghosh, SS Kulkarni - The Journal of Organic Chemistry, 2021 - ACS Publications
Reported herein is the total synthesis of the trisaccharide repeating unit of Streptococcus
pneumoniae zwitterionic polysaccharide Sp1 containing a rare sugar, 2-acetamido-4-amino …

Synthesis of a Highly Branched Nonasaccharide Chlorella Virus N-Glycan Using a “Counterclockwise” Assembly Approach

S Lin, TL Lowary - Organic Letters, 2020 - ACS Publications
Chloroviruses produce a capsid protein containing N-linked glycans differing in structure
from those found in all other organisms. These species feature a core “hyper-branched” …

Straightforward sequential and one-pot synthesis of a pentasaccharide repeating unit corresponding to the cell wall O-antigen of Shigella boydii type 18

P Shit, A Gucchait, AK Misra - Tetrahedron, 2019 - Elsevier
Synthesis of a pentasaccharide repeating unit corresponding to the cell of wall O-antigen
Shigella boydii type 18 has been achieved by sequential as well as iterative glycosylations …

Chemical synthesis of β-l-Rhamnose containing the pentasaccharide repeating unit of the o-specific polysaccharide from a halophilic bacterium halomonas ventosae …

D Pal, B Mukhopadhyay - The Journal of Organic Chemistry, 2021 - ACS Publications
Total synthesis of the pentasaccharide repeating unit of the OPS from Halomonas ventosae
RU5S2EL is accomplished through a [3+ 2] block strategy. Picoloyl-induced hydrogen-bond …