[HTML][HTML] Intestinal barrier damage, systemic inflammatory response syndrome, and acute lung injury: A troublesome trio for acute pancreatitis

P Ge, Y Luo, CS Okoye, H Chen, J Liu, G Zhang… - Biomedicine & …, 2020 - Elsevier
Severe acute pancreatitis (SAP), a serious inflammatory disease of the pancreas, can easily
lead to systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction …

Multifactorial scores and biomarkers of prognosis of acute pancreatitis: applications to research and practice

P Silva-Vaz, AM Abrantes, M Castelo-Branco… - International journal of …, 2020 - mdpi.com
Acute pancreatitis (AP) is a severe inflammation of the pancreas presented with sudden
onset and severe abdominal pain with a high morbidity and mortality rate, if accompanied by …

LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner

WT Wang, H Ye, PP Wei, BW Han, B He… - Journal of hematology & …, 2016 - Springer
Abstract Background Long non-coding RNAs (lncRNAs) are known to play important roles in
different cell contexts, including cancers. However, little is known about lncRNAs in …

The mechanism of lung and intestinal injury in acute pancreatitis: a review

D Liu, L Wen, Z Wang, Y Hai, D Yang, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Acute pancreatitis (AP), as a common cause of clinical acute abdomen, often leads to multi-
organ damage. In the process of severe AP, the lungs and intestines are the most easily …

[HTML][HTML] Cashew (Anacardium occidentale L.) Nuts Modulate the Nrf2 and NLRP3 Pathways in Pancreas and Lung after Induction of Acute Pancreatitis by Cerulein

M Cordaro, R Fusco, R D'Amico, R Siracusa… - Antioxidants, 2020 - mdpi.com
Background: One of the most common co-morbidities, that often leads to death, associated
with acute pancreatitis (AP) is represented by acute lung injury (ALI). While many aspects of …

ROS and intracellular ion channels

K Kiselyov, S Muallem - Cell Calcium, 2016 - Elsevier
Oxidative stress is a well-known driver of numerous pathological processes involving protein
and lipid peroxidation and DNA damage. The resulting increase of pro-apoptotic pressure …

Borneol protects against cerulein‐induced oxidative stress and inflammation in acute pancreatitis mice model

S Bansod, S Chilvery, MA Saifi, TJ Das… - Environmental …, 2021 - Wiley Online Library
Borneol is a commonly used flavouring substance in traditional Chinese medicine, which
possesses several pharmacological activities including analgesic, antiinflammatory, and …

Baicalin inhibits necroptosis by decreasing oligomerization of phosphorylated MLKL and mitigates caerulein-induced acute pancreatitis in mice

YT Huang, QQ Liang, HR Zhang, SY Chen… - International …, 2022 - Elsevier
Necroptosis is a form of regulated necrosis mainly controlled by receptor-interacting protein
kinases 3 (RIPK3) and mixed lineage kinase domain-like protein (MLKL). Necroptosis has …

Metformin ameliorates 5-fluorouracil-induced intestinal injury by inhibiting cellular senescence, inflammation, and oxidative stress

J Xia, J Chen, MK Vashisth, Y Ge, Q Dai, S He… - International …, 2022 - Elsevier
Fluorouracil (5-Fu), which inhibits metabolism, is an essential part of the first-line treatment
of colorectal cancer but causes severe side effects, including nausea, vomiting, anorexia …

Triptolide suppresses NF-κB-mediated inflammatory responses and activates expression of Nrf2-mediated antioxidant genes to alleviate caerulein-induced acute …

J Yang, X Tang, X Ke, Y Dai, J Shi - International journal of molecular …, 2022 - mdpi.com
Triptolide (TP), the main active ingredient of Tripterygium wilfordii Hook. f., displays potent
anti-inflammatory, antioxidant, and antiproliferative activities. In the present study, the effect …