Developmental and epileptic encephalopathies: from genetic heterogeneity to phenotypic continuum

R Guerrini, V Conti, M Mantegazza… - Physiological …, 2023 - journals.physiology.org
Developmental and epileptic encephalopathies (DEEs) are a heterogeneous group of
disorders characterized by early-onset, often severe epileptic seizures and EEG …

[HTML][HTML] West syndrome: a comprehensive review

P Pavone, A Polizzi, SD Marino, G Corsello… - Neurological …, 2020 - Springer
Since its first clinical description (on his son) by William James West (1793–1848) in 1841,
and the definition of the classical triad of (1) infantile spasms;(2) hypsarrhythmia, and (3) …

Эпилепсия у детей и взрослых женщин и мужчин

ВА Карлов - 2019 - elibrary.ru
В руководстве представлены результаты 60-летней работы автора в области детской
и взрослой неврологии и эпилептологии. Впервые эпилептология представлена в …

Infantile spasms: outcome in clinical studies

R Riikonen - Pediatric neurology, 2020 - Elsevier
Children with infantile spasms are likely to have a poor outcome. Outcome measures for
infantile spasms include primary response to treatment, relapse of spasms, neurological …

A population‐based cost‐effectiveness study of early genetic testing in severe epilepsies of infancy

KB Howell, S Eggers, K Dalziel, J Riseley… - …, 2018 - Wiley Online Library
Objective The severe epilepsies of infancy (SEI) are a devastating group of disorders that
pose a major care and economic burden on society; early diagnosis is critical for optimal …

West syndrome: a review and guide for paediatricians

R D'Alonzo, D Rigante, E Mencaroni… - Clinical drug …, 2018 - Springer
West syndrome (WS), also known as infantile spasms, occurs in infancy with a peak
between 4 and 7 months. Spasms, neurodevelopmental regression and hypsarrhythmia on …

Focal cortical dysplasia: an update on diagnosis and treatment

R Guerrini, C Barba - Expert Review of Neurotherapeutics, 2021 - Taylor & Francis
ABSTRACT Introduction Focal cortical dysplasias (FCDs) represent the most common
etiology in pediatric drug-resistant focal epilepsies undergoing surgical treatment. The …

The impact of hypsarrhythmia on infantile spasms treatment response: observational cohort study from the National Infantile Spasms Consortium

ST Demarest, RA Shellhaas, WD Gaillard, C Keator… - …, 2017 - Wiley Online Library
Summary Objective The multicenter National Infantile Spasms Consortium prospective
cohort was used to compare outcomes and phenotypic features of patients with infantile …

[HTML][HTML] Management of infantile spasms

GR Nelson - Translational pediatrics, 2015 - ncbi.nlm.nih.gov
West syndrome, or infantile spasms syndrome is a frequently catastrophic infantile epileptic
encephalopathy with a variety of etiologies. Despite the heterogeneous nature of causes of …

Scalp EEG interictal high frequency oscillations as an objective biomarker of infantile spasms

H Nariai, SA Hussain, D Bernardo, H Motoi… - Clinical …, 2020 - Elsevier
Objective To investigate the diagnostic utility of high frequency oscillations (HFOs) via scalp
electroencephalogram (EEG) in infantile spasms. Methods We retrospectively analyzed …