Diffuse large B-cell lymphoma: R-CHOP failure—what to do?

B Coiffier, C Sarkozy - Hematology 2014, the American Society …, 2016 - ashpublications.org
Although rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-
CHOP) is the standard treatment for patients with diffuse large B-cell lymphoma (DLBCL),∼ …

Management of relapsed/refractory DLBCL

C Sarkozy, LH Sehn - Best Practice & Research Clinical Haematology, 2018 - Elsevier
Diffuse large B cell lymphoma represents the most common type of non-Hodgkin lymphoma.
Although the curability rate is high, around 40% of patients will relapse or exhibit refractory …

[HTML][HTML] ESMO Consensus Conference on malignant lymphoma: general perspectives and recommendations for the clinical management of the elderly patient with …

C Buske, M Hutchings, M Ladetto, V Goede, U Mey… - Annals of …, 2018 - Elsevier
Abstract The European Society for Medical Oncology (ESMO) consensus conference on
mature B cell lymphomas and chronic lymphocytic leukaemia (CLL) was held on 20 June …

[HTML][HTML] New treatment options in elderly patients with diffuse large B-cell lymphoma

A Arcari, F Cavallo, B Puccini, D Vallisa - Frontiers in Oncology, 2023 - frontiersin.org
Most patients with Diffuse Large B-cell Lymphoma (DLBCL) are old (> 65 years of age) and
this population is expected to increase in the following years. A simplified geriatric …

Real‐life experience with the combination of polatuzumab vedotin, rituximab, and bendamustine in aggressive B‐cell lymphomas

M Dimou, SG Papageorgiou… - Hematological …, 2021 - Wiley Online Library
Transplant‐ineligible relapsed/refractory (rr) diffuse large B‐cell lymphoma (DLBCL)
patients represent an unmet medical need. Polatuzumab vedotin (Pola), an anti‐CD79b …

Emerging therapies for the treatment of relapsed or refractory diffuse large B cell lymphoma

P Skrabek, S Assouline, A Christofides, D MacDonald… - Current …, 2019 - mdpi.com
Diffuse large B cell lymphoma (DLBCL) is an aggressive non-Hodgkin lymphoma,
accounting for approximately 30% of lymphoma cases in Canada. Although most patients …

[HTML][HTML] Multidimensional results and reflections on CAR-T: the Italian evidence

E Foglia, E Garagiola, V Ladisa, A Rambaldi… - International Journal of …, 2023 - mdpi.com
The present study aims at defining the economic and organizational impacts of the
introduction of chimeric antigen receptor T-cell therapy (CAR-T) in Italy, for the management …

Diffuse large B-cell lymphoma in the elderly: standard treatment and new perspectives

A Chiappella, A Castellino, M Nicolosi… - Expert review of …, 2017 - Taylor & Francis
Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most common histotype in non
Hodgkin lymphoma, with a peak incidence in the sixth decade. The standard treatment for …

Durvalumab as monotherapy and in combination therapy in patients with lymphoma or chronic lymphocytic leukemia: The FUSION NHL 001 trial

C Casulo, A Santoro, G Cartron, K Ando… - Cancer …, 2023 - Wiley Online Library
Background Studies suggest that immune checkpoint inhibitors may represent a promising
strategy for boosting immune responses and improving the antitumor activity of standard …

[HTML][HTML] Innovative therapeutic strategy for B-cell malignancies that combines obinutuzumab and cytokine-induced killer cells

A Dalla Pietà, E Cappuzzello, P Palmerini… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Patients affected by aggressive B-cell malignancies who are resistant to
primary or salvage chemoimmunotherapy have an extremely poor prognosis and limited …