[HTML][HTML] Mitochondrial dysfunction in cardiac diseases and therapeutic strategies

Y Huang, B Zhou - Biomedicines, 2023 - mdpi.com
Mitochondria are the main site of intracellular synthesis of ATP, which provides energy for
various physiological activities of the cell. Cardiomyocytes have a high density of …

[HTML][HTML] The mechanism of ferroptosis and its related diseases

S Feng, D Tang, Y Wang, X Li, H Bao, C Tang… - Molecular …, 2023 - Springer
Ferroptosis, a regulated form of cellular death characterized by the iron-mediated
accumulation of lipid peroxides, provides a novel avenue for delving into the intersection of …

[HTML][HTML] Atherosclerotic plaque vulnerability quantification system for clinical and biological interpretability

G Zhang, X Cui, Z Qin, Z Wang, Y Lu, Y Xu, S Xu… - Iscience, 2023 - cell.com
Acute myocardial infarction dominates coronary artery disease mortality. Identifying bio-
signatures for plaque destabilization and rupture is important for preventing the transition …

[HTML][HTML] Ferroptosis in cardiovascular disease

G Liu, X Xie, W Liao, S Chen, R Zhong, J Qin… - Biomedicine & …, 2024 - Elsevier
In the 21st century, cardiovascular disease (CVD) has become one of the leading causes of
death worldwide. The prevention and treatment of CVD remain pressing scientific issues …

Combining idebenone and rosuvastatin prevents atherosclerosis by suppressing oxidative stress and NLRP3 inflammasome activation

W Yu, W Jiang, W Wu, G Wang, D Zhao, C Yan… - European Journal of …, 2023 - Elsevier
Atherosclerosis is a progressive inflammatory disease activated by excessive oxidized low-
density lipoprotein (ox-LDL). Statins are the first-line choice to reduce the risk of …

Differential expression profiles of plasma exosomal microRNAs in dilated cardiomyopathy with chronic heart failure

L Zhang, G Zhang, Y Lu, J Gao, Z Qin… - Journal of Cellular …, 2023 - Wiley Online Library
As one of the most prevalent heritable cardiovascular diseases, dilated cardiomyopathy
(DCM) induces cardiac insufficiency and dysfunction. Although genetic mutation has been …

[HTML][HTML] Ferroptosis, a Regulated Form of Cell Death, as a Target for the Development of Novel Drugs Preventing Ischemia/Reperfusion of Cardiac Injury …

VV Ryabov, LN Maslov, EV Vyshlov… - International Journal of …, 2024 - mdpi.com
The hospital mortality in patients with ST-segment elevation myocardial infarction (STEMI) is
about 6% and has not decreased in recent years. The leading cause of death of these …

[HTML][HTML] An assessment system for clinical and biological interpretability in ulcerative colitis

S Zhang, G Zhang, W Wang, SB Guo, P Zhang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) is a serious inflammatory bowel disease (IBD) with high morbidity and
mortality worldwide. As the traditional diagnostic techniques have various limitations in the …

[HTML][HTML] Exploring the Neuroprotective Effects of Lithium in Ischemic Stroke: A literature review

W Wang, D Lu, Y Shi, Y Wang - International Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Ischemic stroke ranks among the foremost clinical causes of mortality and disability,
instigating neuronal degeneration, fatalities, and various sequelae. While standard …

[HTML][HTML] Molecular subtypes of ischemic heart disease based on circadian rhythm

Z Zhou, G Zhang, Z Wang, Y Xu, H Qin, H Zhang… - Scientific Reports, 2024 - nature.com
Coronary atherosclerotic heart disease (CAD) is among the most prevalent chronic diseases
globally. Circadian rhythm disruption (CRD) is closely associated with the progression of …