The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

Bacteriophages are enigmatic entities that defy definition. Classically, they are specialist
viruses that exclusively parasitize bacterial hosts. Yet this definition becomes limiting when …

Crosstalk between gut and brain has long been appreciated in health and disease, and the
gut microbiota is a key player in communication between these two distant organs. Yet, the …

Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Gut microbiota disorders damage the intestinal barrier, which causes intestinal disease.
Thus, we screened the microbiota with significant changes using an in situ malignant …

Weaning stress induces intestinal barrier dysfunction and immune dysregulation in
mammals. Various interventions based on the modulation of intestinal microbiota have been …

The treatment outcomes of oral medications against ulcerative colitis (UC) have long been
restricted by low drug accumulation in the colitis mucosa and subsequent unsatisfactory …

Cardiometabolic disease comprises cardiovascular and metabolic dysfunction and
underlies the leading causes of morbidity and mortality, both within the United States and …

Propionate is a short-chain fatty acid that is generated upon microbiome-mediated fiber
fermentation in the intestine. By modulating immune and metabolic pathways, propionate …

The intestinal lumen is filled with diverse chemical and physical stimuli. Intestinal epithelial
cells sense these stimuli and signal to enteric neurons which coordinate a range of …