[HTML][HTML] Peripheral markers of depression

A Nobis, D Zalewski, N Waszkiewicz - Journal of clinical medicine, 2020 - mdpi.com
Major Depressive Disorder (MDD) is a leading cause of disability worldwide, creating a high
medical and socioeconomic burden. There is a growing interest in the biological …

A comprehensive review of monoamine oxidase inhibitors as Anti-Alzheimer's disease agents: A review

S Manzoor, N Hoda - European journal of medicinal chemistry, 2020 - Elsevier
Monoamine oxidases (MAO-A and MAO-B) are mammalian flavoenzyme, which catalyze the
oxidative deamination of several neurotransmitters like norepinephrine, dopamine, tyramine …

[HTML][HTML] NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression

S Li, Y Sun, M Song, Y Song, Y Fang, Q Zhang, X Li… - JCI insight, 2021 - ncbi.nlm.nih.gov
Emerging evidence suggests that astrocyte loss is one of the most important pathological
features in the hippocampus of patients with major depressive disorder (MDD) and …

[HTML][HTML] Digital health tools for the passive monitoring of depression: a systematic review of methods

V De Angel, S Lewis, K White, C Oetzmann… - NPJ digital …, 2022 - nature.com
The use of digital tools to measure physiological and behavioural variables of potential
relevance to mental health is a growing field sitting at the intersection between computer …

[HTML][HTML] The identification, assessment and management of difficult-to-treat depression: an international consensus statement

RH McAllister-Williams, C Arango, P Blier… - Journal of Affective …, 2020 - Elsevier
Background Many depressed patients are not able to achieve or sustain symptom remission
despite serial treatment trials–often termed “treatment resistant depression”. A broader …

A phase 2 trial of inhaled nitrous oxide for treatment-resistant major depression

P Nagele, BJ Palanca, B Gott, F Brown… - Science translational …, 2021 - science.org
Nitrous oxide at 50% inhaled concentration has been shown to improve depressive
symptoms in patients with treatment-resistant major depression (TRMD). Whether a lower …

[HTML][HTML] Sex differences in the blood–brain barrier: implications for mental health

L Dion-Albert, LB Binder, B Daigle, A Hong-Minh… - Frontiers in …, 2022 - Elsevier
Prevalence of mental disorders, including major depressive disorder (MDD), bipolar
disorder (BD) and schizophrenia (SZ) are increasing at alarming rates in our societies …

Findings from world mental health surveys of the perceived helpfulness of treatment for patients with major depressive disorder

MG Harris, AE Kazdin, WT Chiu, NA Sampson… - JAMA …, 2020 - jamanetwork.com
Importance The perceived helpfulness of treatment is an important patient-centered
measure that is a joint function of whether treatment professionals are perceived as helpful …

Is subthreshold depression in adolescence clinically relevant?

BK Noyes, DP Munoz, S Khalid-Khan, E Brietzke… - Journal of affective …, 2022 - Elsevier
Background Subthreshold depression is highly prevalent in adolescence, but compared to
major depressive disorder, the clinical impact is under-researched. The aim of this review …

Results of the European Group for the Study of Resistant Depression (GSRD)—basis for further research and clinical practice

L Bartova, M Dold, A Kautzky, C Fabbri… - The World Journal of …, 2019 - Taylor & Francis
Objectives: The overview outlines two decades of research from the European Group for the
Study of Resistant Depression (GSRD) that fundamentally impacted evidence-based …