This article describes a procedure to prepare a raft-like intracellular membrane fraction
enriched for the trans-Golgi network (TGN) and endosomal compartments. The initial step in …

Lipid rafts consisting of ergosterol and sphingolipids in the lipid membrane of cells play
important roles in various cellular processes. However, the functions of sphingolipids and …

Many studies have reported metabolomic analysis of different bio-specimens from
Parkinson's disease patients. However, inconsistencies in reported metabolite concentration …

Traumatic brain injury (TBI) can lead to neurodegenerative diseases such as Alzheimer's
disease (AD) through mechanisms that remain incompletely characterized. Similar to AD …

Alkylphospholipid (APL) analogues are promising candidates in the search for treatments for
cancer. In contrast to standard chemotherapeutic drugs, these lipophilic agents target the …

Cardiovascular diseases (CVD) remain the leading cause of death in industrialized
countries. One of the most significant risk factors for atherosclerosis is hypercholesterolemia …

Аннотация Наиболее клинически значимым фактором риска развития сердечно-
сосудистых заболеваний (ССЗ) является нарушение липидного обмена. В процессе …

The Fatty acid hydroxylase (FAH) superfamily in plant is a broad group of proteins
comprising carotene and fatty acid hydroxylases, and sterol desaturases. Favourable allele …

Cardiolipidology–a new direction in cardiology–is developing intensively owing to the
method of mass spectrometry. This method has acquired particular importance for the …

A metabolomics profiling approach was conducted to identify diagnostic biomarkers of PD
from sebum, a non-invasively available biofluid. In this study, we used liquid …