Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …

Interleukin-33 (IL-33) is a nuclear-associated cytokine of the IL-1 family originally described
as a potent inducer of allergic type 2 immunity. IL-33 signals via the receptor ST2, which is …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling,
leading to compromised lung function. Cellular senescence markers are detectable within …

The incidence of food allergies in western countries has increased dramatically in recent
decades. Tolerance to food antigens relies on mucosal CD103+ dendritic cells (DCs), which …

Summary Interleukin (IL)‐33 is a key cytokine involved in type 2 immunity and allergic
airway diseases. Abundantly expressed in lung epithelial cells, IL‐33 plays critical roles in …

Introduction Epidemiological studies demonstrated that cleaning work and frequent use of
cleaning products are risk factors for asthma. Laundry detergents have been reported to …

Background The epithelial cell‐derived danger signal mediators thymic stromal
lymphopoietin (TSLP) and IL‐33 are consistently associated with adaptive Th2 immune …

Women have higher prevalence of asthma compared with men. In asthma, allergic airway
inflammation is initiated by IL-33 signaling through ST2, leading to increased IL-4, IL-5, and …

Innate lymphoid cells (ILCs) represent a distinct branch of the lymphoid lineage composed
of 3 major subpopulations: ILC1, ILC2, and ILC3. ILCs are mainly described as tissue …

Background Atopic diseases, including asthma, exacerbate type 2 immune responses and
involve a number of immune cell types, including regulatory T (Treg) cells and the emerging …