Phenols and phenolic ethers are significant scaffolds recurring both in nature and among
approved small-molecule pharmaceuticals. This compendium presents the first …

Lung cancer remains the leading cause of cancer mortality in men and women in the US
and worldwide. About 90% of lung cancer cases are caused by smoking and the use of …

Purpose The objective of this study was to investigate the antitumor activity, targeting
capability, and mechanism of the developed nanodrug consisting of doxorubicin and …

Photodynamic therapy (PDT) is a treatment modality where light-mediated activation of
photosensitizers in a patient's body leads to the generation of cytotoxic reactive oxygen …

The nuclear receptor superfamily includes transcription factors that transduce steroid, thyroid
and retinoid hormones and other ligands in conjunction with coregulators. To date, over 350 …

Non‐small cell lung cancer (NSCLC) is one of the most deadly cancers worldwide, with poor
prognosis once the disease has progressed past the point at which surgery is a viable …

The measurement of patient-reported outcomes, including health-related quality of life, is a
new initiative which has emerged and grown over the past four decades. Following the …

A series of benzothiazole/isatin linked to 1, 2, 3-triazole moiety and terminal sulpha drugs 5a-
e and 6a-e were synthesized and evaluated for cytotoxic activity against a panel of cancer …

Purpose Peak oxygen consumption (VO 2peak) is an important predictive factor for long-
term prognosis in patients with non-small cell lung cancer (NSCLC). The purpose of this …

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is frequently
mutated or overexpressed in a large number of tumors such as carcinomas or glioblastoma …