Role of oxidative stress in female reproduction

A Agarwal, S Gupta, RK Sharma - Reproductive biology and …, 2005 - Springer
In a healthy body, ROS (reactive oxygen species) and antioxidants remain in balance. When
the balance is disrupted towards an overabundance of ROS, oxidative stress (OS) occurs …

[HTML][HTML] Melatonin and the ovary: physiological and pathophysiological implications

H Tamura, Y Nakamura, A Korkmaz, LC Manchester… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To summarize the role of melatonin in the physiology and pathophysiology of
the ovary. DESIGN: Review of literature. SETTING: University Health Science Center …

Oxidative stress impairs oocyte quality and melatonin protects oocytes from free radical damage and improves fertilization rate

H Tamura, A Takasaki, I Miwa… - Journal of pineal …, 2008 - Wiley Online Library
We investigated the relationship between oxidative stress and poor oocyte quality and
whether the antioxidant melatonin improves oocyte quality. Follicular fluid was sampled at …

Detection of reactive oxygen species (ROS) and apoptosis in human fragmented embryos.

HW Yang, KJ Hwang, HC Kwon, HS Kim… - Human reproduction …, 1998 - academic.oup.com
In human in-vitro fertilization (IVF)-embryo transfer, the in-vitro culture environment differs
from in-vivo conditions in that the oxygen concentration is higher, and in such conditions the …

Andrology lab corner*: role of oxidative stress and antioxidants in andrology and assisted reproductive technology

SC Sikka - Journal of andrology, 2004 - Wiley Online Library
Twenty-five years ago the first human, Louise Brown, was conceived outside the body, and
this event created a new milestone in the history of mankind and the concept of human in …

Oxidative stress and antioxidants: exposure and impact on female fertility

EH Ruder, TJ Hartman, J Blumberg… - Human reproduction …, 2008 - academic.oup.com
BACKGROUND Reproductive failure is a significant public health concern. Although
relatively little is known about factors affecting fertility and early pregnancy loss, a growing …

Redox considerations in female reproductive function and assisted reproduction: from molecular mechanisms to health implications

A Agarwal, S Gupta, L Sekhon… - Antioxidants & redox …, 2008 - liebertpub.com
Physiological levels of reactive oxygen species (ROS) play an important regulatory role
through various signaling transduction pathways in folliculogenesis, oocyte maturation …

Oxidative stress and its implications in female infertility–a clinician's perspective

A Agarwal, S Gupta, R Sharma - Reproductive biomedicine online, 2005 - Elsevier
Reactive oxygen species (ROS) have a role in the modulation of gamete quality and gamete
interaction. Generation of ROS is inherent in spermatozoa and contaminating leukocytes …

Role of free radicals in female reproductive diseases and assisted reproduction

A Agarwal, SSR Allamaneni - Reproductive biomedicine online, 2004 - Elsevier
Infertility is a common problem experienced by many couples. Numerous treatments are
available for female infertility. However, in some cases, the treatment is empirical in nature …

[HTML][HTML] Effect of oxidative stress in follicular fluid on the outcome of assisted reproductive procedures

EB Pasqualotto, A Agarwal, RK Sharma, VM Izzo… - Fertility and sterility, 2004 - Elsevier
OBJECTIVE (S): To measure levels of lipid peroxidation (LPO) and total antioxidant capacity
(TAC) in the follicular fluid from patients undergoing IVF and to examine the association …