An aortic aneurysm is a dilatation in which the aortic diameter is≥ 3.0 cm. If left untreated,
the aortic wall continues to weaken and becomes unable to withstand the forces of the …

Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …

Aortic dissections and aortic aneurysms are fatal events characterized by structural changes
to the aortic wall. The maximum diameter criterion, typically used for aneurysm rupture risk …

Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of aortic
aneurysm because the histology of thoracic aortic aneurysm (TAA) and abdominal aortic …

Current management of aortic aneurysms relies exclusively on prophylactic operative repair
of larger aneurysms. Great potential exists for successful medical therapy that halts or …

Abdominal aortic aneurysm (AAA) is a potentially life-threatening disorder with a mostly
asymptomatic course where the abdominal aorta is weakened and bulged. Cytokines play …

The developmental origin of vascular smooth muscle cells (VSMCs) has been increasingly
recognized as a major determinant for regional susceptibility or resistance to vascular …

Thoracic aortic aneurysm, as occurs in Marfan syndrome, is generally asymptomatic until
dissection or rupture, requiring surgical intervention as the only available treatment. Here …

Objective—Aortic aneurysm, focal dilation of the aorta, results from impaired integrity of
aortic extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are traditionally known …

OBJECTIVES The goal of this study was to evaluate outcomes of aortic arch replacement
using the frozen elephant trunk (FET) technique after previous proximal and/or distal open or …