Liquid biopsies to monitor and direct cancer treatment in colorectal cancer

G Mauri, PP Vitiello, A Sogari, G Crisafulli… - British Journal of …, 2022 - nature.com
Colorectal cancer (CRC) is one of the most prevalent and deadly cancers worldwide.
Despite recent improvements in treatment and prevention, most of the current therapeutic …

Colorectal cancer biology, diagnosis, and therapeutic approaches

B Dariya, S Aliya, N Merchant, A Alam… - Critical Reviews™ in …, 2020 - dl.begellhouse.com
Colorectal cancer (CRC) is the second most diagnosed disease worldwide. It is the fourth
leading cause of cancer related mortalities. Higher probability for the occurrence of CRC is …

Colorectal cancer: Genetic alterations, novel biomarkers, current therapeutic strategies and clinical trails

M Housini, B Dariya, N Ahmed, A Stevens, H Fiadjoe… - Gene, 2023 - Elsevier
Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …

Cell‐free tumour DNA testing for early detection of cancer–a potential future tool

G Barbany, C Arthur, A Liedén… - Journal of Internal …, 2019 - Wiley Online Library
In recent years, detection of cell‐free tumour DNA (ct DNA) or liquid biopsy has emerged as
an attractive noninvasive methodology to detect cancer‐specific genetic aberrations in …

Proximity hybridization-regulated Crispr/Cas12a-based dual signal amplification strategy for sensitive detection of circulating tumor Dna

M Li, N Luo, X Liao, L Zou - Talanta, 2023 - Elsevier
Circulating tumor DNA (ctDNA) is regarded as an ideal candidate biomarker for the non-
invasive diagnosis of cancer. However, the lack of convenient and reliable detection …

Colorectal adenomas—genetics and searching for new molecular screening biomarkers

A Siskova, K Cervena, J Kral, T Hucl, P Vodicka… - International Journal of …, 2020 - mdpi.com
Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new
cases per year worldwide. CRC outcome is closely related to the respective stage of CRC …

Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis-an update

B Molnár, O Galamb, A Kalmár, BK Barták… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Screening methods for one of the most frequently diagnosed malignancy,
colorectal cancer (CRC), have limitations. Circulating cell-free nucleic acids (cfNA) hold …

Uniform palladium nanosheets for fluorimetric detection of circulating tumor DNA

Y Zhang, H Lu, F Yang, Y Cheng, W Dai, X Meng… - Analytica Chimica …, 2020 - Elsevier
Fluorescence quenching property of two-dimensional (2D) nanosheets (NSs) have received
extensively attention in the construction of novel biosensing platform. However, the …

Microsatellite instable colorectal adenocarcinoma diagnostics: the advent of liquid biopsy approaches

C Ceccon, V Angerilli, C Rasola, L Procaccio… - Frontiers in …, 2022 - frontiersin.org
The introduction of immunotherapy has revolutionized the oncological targeted therapy
paradigm. Microsatellite instability (MSI) identifies a subgroup of colorectal cancers (CRCs) …

Is measurement of circulating tumor DNA of diagnostic use in patients with thyroid nodules?

M Lupo, R Guttler, Z Geck, TR Tonozzi… - Endocrine Practice, 2018 - Elsevier
ABSTRACT Objective: Circulating tumor DNA (ctDNA), a subset of cell-free DNA (cfDNA), is
a potential biomarker for thyroid cancer. We determined the performance of a ctDNA panel …