Background & Aims Myeloid cells are key regulators of cirrhosis, a major cause of mortality
worldwide. Because stromal cells can modulate the functionality of myeloid cells in vitro …

Exposure to polychlorinated biphenyls (PCBs) has been associated with liver injury in
human cohorts and with nonalcoholic steatohepatitis (NASH) in mice fed a high fat diet …

The primary objective of this research was to create injectable delivery formulations using
Lactotransferrin (LTF) peptide-loaded dextran nanoparticles coated with docosahexaenoic …

Epithelial intercellular adhesion molecule (ICAM)-1 is apically polarized, interacts with, and
guides leukocytes across epithelial barriers. Polarized hepatic epithelia organize their apical …

Considering the relevance of the research of pathogenesis of different liver diseases, we
investigated the possible activity of the IL-23/IL-17 axis on the immunohepatotoxicity of two …

Hemophagocytic lymphohistiocytosis (HLH) is a rare multisystemic hyperinflammatory
disease commonly associated with hepatic dysfunction. Liver injury is mediated by …

Metabolic dysfunction–associated steatotic liver disease (MASLD), formerly known as non-
alcoholic fatty liver disease (NAFLD), has become a major cause of chronic liver disease …

Background & Aims Interleukin (IL)-20 and IL-22 belong to the IL-10 family. IL-10 is a well-
documented anti-inflammatory cytokine while IL-22 is well known for epithelial protection …

Interleukin (IL) 1 superfamily members are a cornerstone of a variety of inflammatory
processes occurring in various organs including the liver. Progression of acute and chronic …

Deltamethrin (DM) is a widely used insecticide that has demonstrated developmental toxicity
in the early life stages of fish. To better characterize the underlying mechanisms, embryos …