Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …

Multiple factors combined are currently recognized as contributors to cognitive decline. The
main independent risk factor for cognitive impairment and dementia is advanced age …

Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised
bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …

While melatonin is known to have protective effects in mitochondria‐related diseases, aging,
and neurodegenerative disorders, there is poor understanding of the effects of melatonin …

Neurons affected in Alzheimer's disease (AD) experience mitochondrial dysfunction and a
bioenergetic deficit that occurs early and promotes the disease-defining amyloid beta …

Impairments in neuronal intracellular calcium (iCa2+) handling may contribute to
Alzheimer's disease (AD) development. Metabolic dysfunction and progressive neuronal …

Our incomplete understanding of the link between Alzheimer's Disease pathology and
symptomatology is a crucial obstacle for therapeutic success. Recently, translational studies …

Mitochondria are associated with various cellular activities critical to homeostasis,
particularly in the nervous system. The plastic architecture of the mitochondrial network and …

Alzheimer disease (AD) is a progressive and deleterious neurodegenerative disorder that
affects mostly the elderly population. At the moment, no effective treatments are available in …