Glucose metabolism is impaired in brain aging and several neurological conditions.
Beneficial effects of ketones have been reported in the context of protecting the aging brain …

Brain metabolism is comprised in Alzheimer's disease (AD) and Parkinson's disease (PD).
Since the brain primarily relies on metabolism of glucose, ketone bodies, and amino acids …

Most of the energy we get to spend is furnished by mitochondria, minuscule living structures
sitting inside our cells or dispatched back and forth within them to where they are needed …

J. Neurochem.(2011) 118, 611–615. Abstract The structure and function of the
hippocampus, a brain region critical for learning and memory, is impaired by obesity and …

We examined the expression of genes related to brain energy metabolism and particularly
those encoding glia (astrocyte)-specific functions in the dorsal hippocampus subsequent to …

Neurodegenerative diseases are the most common diseases of the nervous system in
elderly people, which are currently incurable and cause great burden to families and …

Potential biomarkers for Alzheimer's disease (AD) include amyloid β1–42 (Aβ1–42), t-Tau, p-
Tau181, neurofilament light chain (NFL), and neuroimaging biomarkers. Their combined use …

Mitochondrial dysfunctions significantly contribute to the pathogenesis of Alzheimer's
disease (AD). Here, we studied the relationship between AD and changes in the …

Long-term exposure to environmental aluminum was found to be related to the occurrence
and development of neurodegenerative diseases. Energy metabolism disorders, one of the …

Citrate synthase is a key mitochondrial enzyme that utilizes acetyl-CoA and oxaloacetate to
form citrate in the mitochondrial membrane, which participates in energy production in the …