[HTML][HTML] Aging and functional brain networks
D Tomasi, ND Volkow - Molecular psychiatry, 2012 - nature.com
Aging is associated with changes in human brain anatomy and function and cognitive
decline. Recent studies suggest the aging decline of major functional connectivity hubs in …
decline. Recent studies suggest the aging decline of major functional connectivity hubs in …
[HTML][HTML] Energy intake and exercise as determinants of brain health and vulnerability to injury and disease
MP Mattson - Cell metabolism, 2012 - cell.com
Evolution favored individuals with superior cognitive and physical abilities under conditions
of limited food sources, and brain function can therefore be optimized by intermittent dietary …
of limited food sources, and brain function can therefore be optimized by intermittent dietary …
[HTML][HTML] The ketogenic diet as a treatment paradigm for diverse neurological disorders
CE Stafstrom, JM Rho - Frontiers in pharmacology, 2012 - frontiersin.org
Dietary and metabolic therapies have been attempted in a wide variety of neurological
diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson …
diseases, including epilepsy, headache, neurotrauma, Alzheimer disease, Parkinson …
Role of RAGE in Alzheimer's disease
Z Cai, N Liu, C Wang, B Qin, Y Zhou, M Xiao… - Cellular and molecular …, 2016 - Springer
Receptor for advanced glycation end products (RAGE) is a receptor of the immunoglobulin
super family that plays various important roles under physiological and pathological …
super family that plays various important roles under physiological and pathological …
Adaptive responses of neuronal mitochondria to bioenergetic challenges: Roles in neuroplasticity and disease resistance
SM Raefsky, MP Mattson - Free Radical Biology and Medicine, 2017 - Elsevier
An important concept in neurobiology is “neurons that fire together, wire together” which
means that the formation and maintenance of synapses is promoted by activation of those …
means that the formation and maintenance of synapses is promoted by activation of those …
[HTML][HTML] Beyond weight loss: a review of the therapeutic uses of very-low-carbohydrate (ketogenic) diets
Very-low-carbohydrate diets or ketogenic diets have been in use since the 1920s as a
therapy for epilepsy and can, in some cases, completely remove the need for medication …
therapy for epilepsy and can, in some cases, completely remove the need for medication …
[HTML][HTML] Contribution of the Nrf2 pathway on oxidative damage and mitochondrial failure in Parkinson and Alzheimer's disease
F Villavicencio Tejo, RA Quintanilla - Antioxidants, 2021 - mdpi.com
The increase in human life expectancy has become a challenge to reduce the deleterious
consequences of aging. Nowadays, an increasing number of the population suffer from age …
consequences of aging. Nowadays, an increasing number of the population suffer from age …
[HTML][HTML] Promotion of astrocyte-neuron glutamate-glutamine shuttle by SCFA contributes to the alleviation of Alzheimer's disease
Y Sun, H Zhang, X Zhang, W Wang, Y Chen, Z Cai… - Redox Biology, 2023 - Elsevier
The brain is particularly susceptible to oxidative damage which is a key feature of several
neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD) …
neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD) …
Metabolic inflammation—a role for hepatic inflammatory pathways as drivers of comorbidities in nonalcoholic fatty liver disease?
N Gehrke, JM Schattenberg - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is a global and growing health concern. Emerging
evidence points toward metabolic inflammation as a key process in the fatty liver that …
evidence points toward metabolic inflammation as a key process in the fatty liver that …
[HTML][HTML] Activity dependent degeneration explains hub vulnerability in Alzheimer's disease
W De Haan, K Mott, ECW Van Straaten, P Scheltens… - 2012 - journals.plos.org
Brain connectivity studies have revealed that highly connected 'hub'regions are particularly
vulnerable to Alzheimer pathology: they show marked amyloid-β deposition at an early …
vulnerable to Alzheimer pathology: they show marked amyloid-β deposition at an early …