A wealth of research over the past 2 decades has expanded our understanding of the impact
of early‐life adversity on physiological function and, consequently, health and wellbeing in …

Centralized pain syndromes are associated with changes within the central nervous system
that amplify peripheral input and/or generate the perception of pain in the absence of a …

The importance of the modulation of pain by emotion is now widely recognised. In particular,
stress and anxiety, depending on their nature, duration and intensity, can exert potent, but …

Pain in infancy influences pain reactivity in later life, but how and why this occurs is poorly
understood. Here we review the evidence for developmental plasticity of nociceptive …

Abstract Purpose of Review Patients with chronic pain, especially primary or centralized
pain, have elevated rates of psychosocial trauma and intrapersonal or intrapsychic conflict …

Fibromyalgia (FM) is a complex syndrome, with an indefinite aetiology and intricate
pathophysiology that affects 2–3% of the world population. From the beginning of the 2000s …

Objective Multiple and specific types of childhood adverse events are risk factors for chronic
pain conditions. Although both can covary, no study has evaluated one aspect while …

African Americans disproportionately suffer more severe and debilitating morbidity from
chronic pain than do non-Hispanic Whites. These differences may arise from differential …

This article explores the multifactorial relationship between mastication and cognition, with a
focus on dementia. Older persons, especially those with dementia, are at great risk of …

Objective Previous research has shown a detrimental effect of child victimization (CV) on
physical disease and mortality. Additionally, individuals with adverse experiences in …