A hyperspectral imaging system using a liquid-crystal tunable filter (LCTF) was constructed
for the purpose of in vivo optical imaging of oral neoplasia. The system operates in …

In the past several decades, fluorescence spectroscopy has had a dramatic effect on many
different fields of research. One field that has seen significant advancements is biomedical …

Oral cancer is a rising health issue in many low and middle income countries (LMIC).
Proposed is an implementation of autofluorescence imaging (AFI) and white light imaging …

Optical methods such as reflectance and fluorescence spectroscopy are being investigated
for their potential to aid cancer detection in a quantitative, minimally invasive manner …

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Background Laser‐induced autofluorescence (LIAF) and diffuse reflectance (DR) were
collectively used in this clinical study to improve early oral cancer diagnosis and tissue …

Abstract Studies of 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PPIX)
fluorescence have shown a sensitivity of 95-100% for oral cancer diagnosis, but the …

Using the hamster cheek pouch carcinogenesis model, we explore which fluorescence
excitation wavelengths are useful for the detection of neoplasia. 42 hamsters were treated …

Objective Multiphoton autofluorescence microscopy (MPAM) has shown potential in
identifying features that are directly related to tissue microstructural and biochemical …

In one aspect, the invention provides a diagnostic method for identifying psoriatic plaques in
which Porphyrins, particularly protoporphyrin IX, are elevated as compared to normal skin …