[HTML][HTML] PI3K/AKT/mTOR signaling transduction pathway and targeted therapies in cancer
A Glaviano, ASC Foo, HY Lam, KCH Yap, W Jacot… - Molecular cancer, 2023 - Springer
Abstract The PI3K/AKT/mTOR (PAM) signaling pathway is a highly conserved signal
transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell …
transduction network in eukaryotic cells that promotes cell survival, cell growth, and cell …
Receptor tyrosine kinases: biological functions and anticancer targeted therapy
N Zhang, Y Li - MedComm, 2023 - Wiley Online Library
Receptor tyrosine kinases (RTKs) are a class of protein kinases that play crucial roles in
various cellular processes, including cell migration, morphological differentiation, cell …
various cellular processes, including cell migration, morphological differentiation, cell …
[HTML][HTML] A real-world pharmacovigilance study of FDA adverse event reporting system events for Capmatinib
Y Qi, J Li, S Lin, S Wu, K Chai, X Jiang, J Qian… - Scientific Reports, 2024 - nature.com
Capmatinib is a potent selective mesenchymal-epithelial transition inhibitor approved in
2020 for the treatment of metastatic non-small cell lung cancer. As real-world evidence is …
2020 for the treatment of metastatic non-small cell lung cancer. As real-world evidence is …
[HTML][HTML] The Different Roles of MET in the Development and Treatment of Cancer
J Mollerup, JT Jørgensen - Cancers, 2023 - mdpi.com
This Special Issue features contributions from leading international researchers in the field
of MET (hepatocyte growth factor (HGF) receptor) biology and therapeutics. Recent …
of MET (hepatocyte growth factor (HGF) receptor) biology and therapeutics. Recent …