Adrenal cortical carcinoma (ACC) is a rare and aggressive malignancy that poses
challenging issues regarding the diagnostic workup. Indeed, no presurgical technique or …

Predisposing syndromes associated with an increased risk of Wilms tumor (WT) are
responsible for 9–17% of all cases of the malignancy. Due to an earlier age at WT diagnosis …

Developing synchronous bilateral Wilms tumor suggests an underlying (epi) genetic
predisposition. Here, we evaluate this predisposition in 68 patients using whole exome or …

Beckwith‐Wiedemann syndrome (BWS) is the most common epigenetic overgrowth and
cancer predisposition disorder. Due to both varying molecular defects involving …

Objectives: Summarize the typical clinical presentation of a patient with Wilms tumor. Outline
the differential diagnosis of abdominal masses in children. Identify treatment considerations …

Background Constitutional or somatic mosaic epimutations are increasingly recognized as a
mechanism of gene dysregulation resulting in cancer susceptibility. Beckwith‐Wiedemann …

Purpose It is well documented that patients with Beckwith–Wiedemann spectrum (BWS)
have a significantly higher risk of developing Wilms tumor (WT) than the general population …

Simple Summary It is well known that different cancer predisposition syndromes are
associated with characteristic WT-features. The following findings from our retrospective …

Background Beckwith-Wiedemann Syndrome (BWS) is characterised by overgrowth and
tumour predisposition. While multiple epigenetic and genetic mechanisms cause BWS, the …

Simple Summary Beckwith–Wiedemann Syndrome (BWS) is one of the five most frequent
syndromes predisposing to Wilms tumor (WT). BWS can be underdiagnosed if the …