Advances in the carbonic anhydrase (CA, EC 4.2. 1.1) research over the last three decades
are presented, with an emphasis on the deciphering of the activation mechanism, the …

The mitochondrial isoforms VA/VB of metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
are involved in metabolic processes, such as de novo lipogenesis and fatty acid …

Introduction Several isoforms of the metalloenzyme carbonic anhydrase (CA, EC 4.2. 1.1)
are connected with tumorigenesis. Hypoxic tumors overexpress CA IX and XII as a …

Introduction Cancer affects an increasing number of patients each year with an
unacceptable death toll worldwide. A new therapeutic approach to combat tumors consists …

The lacrimal gland is of central interest in ophthalmology both as the source of the aqueous
component of tear fluid and as the site of autoimmune pathology in the context of Sjogren's …

Abstract Carbonic anhydrase V (CA V), a mitochondrial enzyme, was first isolated from
guinea‐pig liver and subsequently identified in mice and humans. Later, studies revealed …

Carbonic anhydrases (CAs, EC 4.2. 1.1) are widespread metalloenzymes in organisms in all
life kingdoms, being involved in pH regulation, metabolic processes and many other …

Background: Brucellosis is a pervasive zoonotic disease caused by various Brucella
species. It mainly affects livestock and wildlife and poses significant public health threats …

A one-pot two-step protocol was developed for the synthesis of a series of novel 4-
cyanamidobenzenesulfonamides from easily accessible methyl (4-sulfamoylphenyl) …

Tuberculosis (TB) is a serious infectious disease caused by Mycobacterium tuberculosis
(MTB) and a significant health concern worldwide. The main threat to the elimination of TB is …