Dysregulation of adult hippocampal neuroplasticity in major depression: pathogenesis and therapeutic implications
Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …
State-dependent effects of neural stimulation on brain function and cognition
Invasive and non-invasive brain stimulation methods are widely used in neuroscience to
establish causal relationships between distinct brain regions and the sensory, cognitive and …
establish causal relationships between distinct brain regions and the sensory, cognitive and …
Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating
Cravings that precede loss of control (LOC) over food consumption present an opportunity
for intervention in patients with the binge eating disorder (BED). In this pilot study, we used …
for intervention in patients with the binge eating disorder (BED). In this pilot study, we used …
Closed-loop enhancement and neural decoding of cognitive control in humans
Deficits in cognitive control—that is, in the ability to withhold a default pre-potent response in
favour of a more adaptive choice—are common in depression, anxiety, addiction and other …
favour of a more adaptive choice—are common in depression, anxiety, addiction and other …
Toward personalized medicine in connectomic deep brain stimulation
At the group-level, deep brain stimulation leads to significant therapeutic benefit in a
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
multitude of neurological and neuropsychiatric disorders. At the single-patient level …
Closing the loop in psychiatric deep brain stimulation: physiology, psychometrics, and plasticity
AS Widge - Neuropsychopharmacology, 2024 - nature.com
Deep brain stimulation (DBS) is an invasive approach to precise modulation of
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
psychiatrically relevant circuits. Although it has impressive results in open-label psychiatric …
[HTML][HTML] High-resolution mapping and digital atlas of subcortical regions in the macaque monkey based on matched MAP-MRI and histology
Subcortical nuclei and other deep brain structures are known to play an important role in the
regulation of the central and peripheral nervous systems. It can be difficult to identify and …
regulation of the central and peripheral nervous systems. It can be difficult to identify and …
[HTML][HTML] Neural interface systems with on-device computing: machine learning and neuromorphic architectures
Highlights•Neural interfaces continue to improve in channel count and form factor.•Low-
power machine learning and neuromorphic processors can be integrated onto neural …
power machine learning and neuromorphic processors can be integrated onto neural …
Local and distant cortical responses to single pulse intracranial stimulation in the human brain are differentially modulated by specific stimulation parameters
Background Electrical neuromodulation via direct electrical stimulation (DES) is an
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
increasingly common therapy for a wide variety of neuropsychiatric diseases. Unfortunately …
Neuromorphic bioelectronic medicine for nervous system interfaces: from neural computational primitives to medical applications
E Donati, G Indiveri - Progress in Biomedical Engineering, 2023 - iopscience.iop.org
Bioelectronic medicine treats chronic diseases by sensing, processing, and modulating the
electronic signals produced in the nervous system of the human body, labeled'neural …
electronic signals produced in the nervous system of the human body, labeled'neural …