Artificial intelligence aids in development of nanomedicines for cancer management

P Tan, X Chen, H Zhang, Q Wei, K Luo - Seminars in cancer biology, 2023 - Elsevier
Over the last decade, the nanomedicine has experienced unprecedented development in
diagnosis and management of diseases. A number of nanomedicines have been approved …

[HTML][HTML] Biomimetic platelet membrane-coated nanoparticles for targeted therapy

H Han, R Bartolo, J Li, MA Shahbazi… - European Journal of …, 2022 - Elsevier
The development of cell membrane-modified biomimetic nanoparticles has extensively
increased during the past years due to their exceptional biocompatibility, evasion from the …

Single extracellular vesicle analysis for early cancer detection

S Ferguson, KS Yang, R Weissleder - Trends in molecular medicine, 2022 - cell.com
Extracellular vesicles (EVs) are actively shed into the circulation from both cancer and host
cells. EVs are emerging as one of the diagnostic frontrunners for early cancer detection …

Enhancing clinical potential of liquid biopsy through a multi-omic approach: A systematic review

G Di Sario, V Rossella, ES Famulari, A Maurizio… - Frontiers in …, 2023 - frontiersin.org
In the last years, liquid biopsy gained increasing clinical relevance for detecting and
monitoring several cancer types, being minimally invasive, highly informative and replicable …

Tumor cell-released kynurenine biases MEP differentiation into megakaryocytes in individuals with cancer by activating AhR–RUNX1

L Zhou, D Wu, Y Zhou, D Wang, H Fu, Q Huang… - Nature …, 2023 - nature.com
Tumor-derived factors are thought to regulate thrombocytosis and erythrocytopenia in
individuals with cancer; however, such factors have not yet been identified. Here we show …

Platelet-derived drug delivery systems: pioneering treatment for cancer, cardiovascular diseases, infectious diseases, and beyond

Y Zhu, L Xu, Y Kang, Q Cheng, Y He, X Ji - Biomaterials, 2024 - Elsevier
Platelets play a critical role as circulating cells in the human body and contribute to essential
physiological processes such as blood clotting, hemostasis, vascular repair, and thrombus …

[HTML][HTML] Hemostasis and cancer: Impact of haemostatic biomarkers for the prediction of clinical outcomes in patients with cancer

F Moik, C Ay - Journal of Thrombosis and Haemostasis, 2022 - Elsevier
Patients with cancer are characterized by a dysregulation of the hemostatic system and
systemic hypercoagulability. Different components of the hemostatic system are involved in …

Inflammation and cancer: from the development of personalized indicators to novel therapeutic strategies

P Ballerini, A Contursi, A Bruno, M Mucci… - Frontiers in …, 2022 - frontiersin.org
Colorectal (CRC) and hepatocellular carcinoma (HCC) are associated with chronic
inflammation, which plays a role in tumor development and malignant progression. An …

Liquid biopsy in lung cancer: biomarkers for the management of recurrence and metastasis

VGP Souza, A Forder, LJ Brockley… - International Journal of …, 2023 - mdpi.com
Liquid biopsies have emerged as a promising tool for the detection of metastases as well as
local and regional recurrence in lung cancer. Liquid biopsy tests involve analyzing a …

Prognostic significance of Hemoglobin, Albumin, Lymphocyte and Platelet (HALP) Score in hepatocellular carcinoma

J Zhou, D Yang - Journal of hepatocellular carcinoma, 2023 - Taylor & Francis
Purpose HALP score consisting of hemoglobin content, albumin content, lymphocyte count,
and platelet count can comprehensively evaluate the inflammatory response and nutritional …