[HTML][HTML] Epigenetic mechanisms involved in melanoma pathogenesis and chemoresistance
The discovery of highly recurrent mutations in melanoma, such as BRAF V600E, completely
changed the clinical management including therapy of melanoma patients. In the era of …
changed the clinical management including therapy of melanoma patients. In the era of …
MicroRNA-139-5p modulates the growth and metastasis of malignant melanoma cells via the PI3K/AKT signaling pathway by binding to IGF1R
C Yang, Z Xia, L Zhu, Y Li, Z Zheng, J Liang, L Wu - Cell Cycle, 2019 - Taylor & Francis
The relation between microRNAs (miRNAs) and malignant melanoma has been
demonstrated in previous studies, while there was little research about miR-139-5p and …
demonstrated in previous studies, while there was little research about miR-139-5p and …
[HTML][HTML] miR‑186 suppressed CYLD expression and promoted cell proliferation in human melanoma
H Qiu, S Yuan, X Lu - Oncology Letters, 2016 - spandidos-publications.com
Previous studies have shown that microRNA‑186 (miR‑186) is overexpressed in various
human cancers and is associated with the regulation of the carcinogenic processes …
human cancers and is associated with the regulation of the carcinogenic processes …
[HTML][HTML] The concept of hormesis in cancer therapy–Is less more?
A Gaya, CA Akle, S Mudan, J Grange - Cureus, 2015 - ncbi.nlm.nih.gov
There has, in recent years, been a paradigm shift in our understanding of the role of the
immune system in the development of cancers. Immune dysregulation, manifesting as …
immune system in the development of cancers. Immune dysregulation, manifesting as …
[HTML][HTML] MicroRNA-342 prohibits proliferation and invasion of melanoma cells by directly targeting zinc-finger E-box-binding Homeobox 1
Q Shi, Q He, J Wei - Oncology Research, 2018 - ncbi.nlm.nih.gov
As documented in numerous studies, microRNAs (miRNAs) play key roles in various
biological processes associated with melanoma occurrence and development. In this study …
biological processes associated with melanoma occurrence and development. In this study …
Vascular endothelial growth factor/semaphorin-3A ratio and SEMA3A expression in cutaneous malignant melanoma
G Lucarini, O Simonetti, R Lazzarini… - Melanoma …, 2020 - journals.lww.com
Breslow thickness and Clark level are still important factors for cutaneous melanoma, but do
not provide a precise prognosis in all cases. It is necessary to find new factors capable of a …
not provide a precise prognosis in all cases. It is necessary to find new factors capable of a …
[HTML][HTML] Molecular signatures associated with tumor-specific immune response in melanoma patients treated with dendritic cell-based immunotherapy
T García-Salum, A Villablanca, F Matthäus, A Tittarelli… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Purpose We previously showed that autologous dendritic cells (DCs) loaded with an
allogeneic heat shock (HS)-conditioned melanoma cell-derived lysate, called TRIMEL …
allogeneic heat shock (HS)-conditioned melanoma cell-derived lysate, called TRIMEL …
[HTML][HTML] Dormancy of growth-stunted malignant melanoma: sustainable and smoldering patterns
C Piérard-Franchimont, T Hermanns-Lê… - Oncology …, 2014 - ncbi.nlm.nih.gov
The presentations of primary and metastatic cutaneous malignant melanoma (CMM) are
very diverse. Evidence increasingly indicates that single CMM cells spread to distant sites …
very diverse. Evidence increasingly indicates that single CMM cells spread to distant sites …