Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

Abstract Purpose of Review The purpose of this literature review was to review the latest
advancements with biologics in rapid drug desensitization. Our methodology was to …

Insulin reactions occur rarely but are of tremendous clinical importance. The first was
reported in 1922 as a callus reaction at the injection site of insufficiently purified bovine …

Abstract The European Medicines Agency (EMA) defines excipients as the constituents of a
pharmaceutical form apart from the active substance. Delayed hypersensitivity reactions …

Лекарственной аллергией страдает более 7% населения. Известны случаи развития
тяжелых угрожающих жизни аллергических реакций. В обзоре представлены …

Diabetes mellitus (DM) is a very common metabolic disorder/disease. The deterioration of β‐
cells by autoimmune system is the hallmark of this disease. Thioredoxin‐Interacting Protein …

An excipient is an inert substance added to a drug to change dissolution or the kinetics of
absorption, improve stability, influence palatability, or create a distinctive appearance. Also …

Background: Insulin is used to treat patients with both type 1 and type 2 diabetes mellitus.
Allergic reac-tions to insulin might be triggered by insulin itself or inactive ingredients in the …

Diabetes mellitus is one of the most prevalent chronic diseases in the USA. If uncontrolled,
diabetes can lead to devastating complications. Diabetes medications and medical devices …

Background: A biosimilar product is expected to exhibit similar safety, efficacy, and quality as
that of the approved reference product. Only a few reports of thorough evaluation of the …