The remarkable plasticity of Schwann cells allows them to adopt the Remak (non-myelin)
and myelin phenotypes, which are specialized to meet the needs of small and large …

The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

The regenerative potential of mammalian peripheral nervous system neurons after injury is
critically limited by their slow axonal regenerative rate. Regenerative ability is influenced by …

Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …

Nerve injury triggers the conversion of myelin and non‐myelin (Remak) Schwann cells to a
cell phenotype specialized to promote repair. Distal to damage, these repair Schwann cells …

Schwann cells respond to nerve injury by cellular reprogramming that generates cells
specialized for promoting regeneration and repair. These repair cells clear redundant …

Peripheral nerve injury (PNI), one of the most common concerns following trauma, can result
in a significant loss of sensory or motor function. Restoration of the injured nerves requires a …

Injured peripheral nerves regenerate their lost axons but functional recovery in humans is
frequently disappointing. This is so particularly when injuries require regeneration over long …

There is consensus that, distal to peripheral nerve injury, myelin and Remak cells
reorganize to form cellular columns, Bungner's bands, which are indispensable for …

Perineural invasion (PNI) is the process of neoplastic invasion of nerves and is an under‐
recognized route of metastatic spread. It is emerging as an important pathologic feature of …