Carbon catabolite repression (CCR) controls the order in which different carbon sources are
metabolized. Although this system is one of the paradigms of the regulation of gene …

The cyclic AMP (cAMP)-dependent catabolite repression effect in Escherichia coli is among
the most intensely studied regulatory processes in biology. However, the physiological …

Bacterial persisters are phenotypic variants that form from the action of stress response
pathways triggering toxin-mediated antibiotic tolerance. Although persisters form during …

The growth of microorganisms involves the conversion of nutrients in the environment into
biomass, mostly proteins and other macromolecules. This conversion is accomplished by …

A classic problem in microbiology is that bacteria display two types of growth behavior when
cultured on a mixture of two carbon sources: the two sources are sequentially consumed …

Rapid identification of both species and even specific strains of human pathogenic bacteria
grown on standard agar has been achieved from the volatiles they produce using a …

Bi-phasic or diauxic growth is often observed when microbes are grown in a chemically
defined medium containing two sugars (for example glucose and lactose). Typically, the two …

It is commonly thought that when multiple carbon sources are available, bacteria metabolize
them either sequentially (diauxic growth) or simultaneously (co-utilization). However, this …

Many microorganisms exhibit nutrient preferences, exemplified by the 'hierarchical'
consumption of certain carbon substrates. Here, we systematically investigate under which …

Chronic and recurrent infections have been attributed to persisters in biofilms, and despite
this importance, the mechanisms of persister formation in biofilms remain unclear. The …