Polymyxin combination therapy for multidrug-resistant, extensively-drug resistant, and difficult-to-treat drug-resistant gram-negative infections: is it superior to …

A Ardebili, A Izanloo, M Rastegar - Expert Review of Anti-infective …, 2023 - Taylor & Francis
Introduction The increasing prevalence of infections with multidrug-resistant (MDR),
extensively-drug resistant (XDR) or difficult-to-treat drug resistant (DTR) Gram-negative …

In Vitro Susceptibility to Ceftazidime-Avibactam and Comparator Antimicrobial Agents of Carbapenem-Resistant Enterobacterales Isolates

TP Lim, JY Ho, JQM Teo, JHC Sim, SH Tan, TT Tan… - Microorganisms, 2023 - mdpi.com
The emergence of carbapenem-resistant Enterobacterales (CRE) has been recognized as a
significant concern globally. Ceftazidime/avibactam (CZA) is a novel β-lactam/β-lactamase …

Current state of antimicrobial stewardship in organ transplantation in Singapore

SJ Chung, Y Liew, WHL Lee, ALH Kwa… - Transplant Infectious …, 2022 - Wiley Online Library
Abstract Background Antibiotic stewardship programs (ASPs) are well established in the
public hospitals in Singapore, but they are not mandatory for transplant programs. Given the …

Selective antibacterial and antibiofilm activity of chlorinated hemicyanine against gram-positive bacteria

N Atac, H Gunduz, I Koc, K Onbasli, M Khan… - … Acta Part A: Molecular …, 2024 - Elsevier
Antibiotic-free therapies are highly needed due to the limited success of conventional
approaches especially against biofilm related infections. In this direction, antimicrobial …

In vitro Activity of Cefepime/Avibactam Against Carbapenem Resistant Klebsiella pneumoniae and Integrative Metabolomics-Proteomics Approach for Resistance …

L Wen, C Luo, X Chen, T Liu, X Li… - Infection and Drug …, 2023 - Taylor & Francis
Purpose We aimed to evaluate the in vitro antibacterial effects of combination of
cefepime/avibactam against carbapenem-resistant Klebsiella pneumonia (CRKP) and …

Evaluation of the in vitro synergy of polymyxin B-based combinations against polymyxin B-resistant gram-negative bacilli

Y Li, S Guo, X Li, Y Yu, B Yan, M Tian, B Xu, H Hu - Microbial Pathogenesis, 2022 - Elsevier
Objectives This study aimed to evaluate the in vitro synergy of polymyxin B (PMB) combined
with 11 other antibiotics against PMB-resistant gram-negative bacilli (GNBs). Methods Thirty …

Genotypic, phenotypic, and in silico analysis of carbapenem-resistant Klebsiella pneumoniae

S Shukla, H Upadhyaya, P Sisodiya, S Kosara… - 2023 - nopr.niscpr.res.in
Due to an increase in serious infections and a lack of efficient therapies, Klebsiella
pneumoniae has recently gained more recognition. The production of carbapenemases is …