[HTML][HTML] Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase …

P Pinton, C Braicu, JP Nougayrede, J Laffitte… - The Journal of …, 2010 - Elsevier
Deoxynivalenol (DON) is a common mycotoxin that contaminates cereals and their by-
products. The gastrointestinal tract is the first physical barrier against ingested food …

Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention

KS Chun, YJ Surh - Biochemical pharmacology, 2004 - Elsevier
Expression of cyclooxygenase-2 (COX-2) has been reported to be elevated in human
colorectal adenocarcinoma and other tumors, including those of breast, cervical, prostate …

Signaling by G-protein-coupled receptor (GPCR): studies on the GnRH receptor

Z Naor - Frontiers in neuroendocrinology, 2009 - Elsevier
Gonadotropin-releasing hormone (GnRH) is the first key hormone of reproduction. GnRH
analogs are extensively used in in vitro fertilization, and treatment of sex hormone …

Activation of p38 mitogen‐activated protein kinase and c‐Jun‐NH2‐terminal kinase by BMP‐2 and their implication in the stimulation of osteoblastic cell differentiation

J Guicheux, J Lemonnier, C Ghayor… - Journal of Bone and …, 2003 - academic.oup.com
Signaling involved in osteoblastic cell differentiation remains largely unknown. This study
further investigates mechanisms involved in BMP‐2‐induced osteoblastic cell differentiation …

[HTML][HTML] Intrinsic disorder in scaffold proteins: getting more from less

MS Cortese, VN Uversky, AK Dunker - Progress in biophysics and …, 2008 - Elsevier
Regulation, recognition and cell signaling involve the coordinated actions of many players.
Signaling scaffolds, with their ability to bring together proteins belonging to common and/or …

Activation of MAPK cascades by G-protein-coupled receptors: the case of gonadotropin-releasing hormone receptor

Z Naor, O Benard, R Seger - Trends in Endocrinology & Metabolism, 2000 - cell.com
G-protein-coupled receptors (GPCRs) are a large group of integral membrane receptors that
transmit signals from a diverse array of external stimuli, including neurotransmitters …

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

KSM Smalley - International journal of cancer, 2003 - Wiley Online Library
During the process of oncogenic transformation, melanoma cells escape from normal growth‐
control mechanisms and acquire the ability to invade surrounding tissues and organs. The …

Kaempferol acts through mitogen‐activated protein kinases and protein kinase B/AKT to elicit protection in a model of neuroinflammation in BV2 microglial cells

SE Park, K Sapkota, S Kim, H Kim… - British journal of …, 2011 - Wiley Online Library
BACKGROUND AND PURPOSE Kaempferol, a dietary flavonoid and phyto‐oestrogen, is
known to have anti‐inflammatory properties. Microglial activation has been implicated in …

Glutathione, stress responses, and redox signaling in lung inflammation

I Rahman, SK Biswas, LA Jimenez… - Antioxidants & redox …, 2005 - liebertpub.com
Changes in the ratio of intracellular reduced and disulfide forms of glutathione (GSH/GSSG)
can affect signaling pathways that participate in various physiological responses from cell …

[HTML][HTML] Quercetin exerts anti-inflammatory effects via inhibiting tumor necrosis factor-α-induced matrix metalloproteinase-9 expression in normal human gastric …

HL Hsieh, MC Yu, LC Cheng, MY Chu… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Gastric injury is the most common digestive system disease worldwide and
involves inflammation, which can lead to gastric ulcer or gastric cancer (GC). Matrix …