[HTML][HTML] Recent advances and clinical translation of liposomal delivery systems in cancer therapy

J Chen, S Hu, M Sun, J Shi, H Zhang, H Yu… - European Journal of …, 2024 - Elsevier
The limitations of conventional cancer treatment are driving the emergence and
development of nanomedicines. Research in liposomal nanomedicine for cancer therapy is …

[HTML][HTML] Fisetin—In search of better bioavailability—From macro to nano modifications: A review

J Szymczak, J Cielecka-Piontek - International Journal of Molecular …, 2023 - mdpi.com
As secondary plant metabolites, polyphenols are abundant in fruits and vegetables. They
are in high demand because of their many health benefits. However, their low bioavailability …

Regulating size and charge of liposomes in microneedles to enhance intracellular drug delivery efficiency in skin for psoriasis therapy

F Qu, Y Sun, D Bi, S Peng, M Li, H Liu… - Advanced …, 2023 - Wiley Online Library
The stratum corneum (SC) and cell membrane are two major barriers that hinder the
therapeutic outcomes of transdermal drug delivery for the treatment of skin diseases. While …

[HTML][HTML] Research status and prospect of non-viral vectors based on siRNA: a review

L Tong, D Liu, Z Cao, N Zheng, C Mao, S Liu… - International journal of …, 2023 - mdpi.com
Gene therapy has attracted much attention because of its unique mechanism of action, non-
toxicity, and good tolerance, which can kill cancer cells without damaging healthy tissues …

[HTML][HTML] Transport of cationic liposomes in a human blood brain barrier model: Role of the stereochemistry of the gemini amphiphile on liposome biological features

B Simonis, D Vignone, OG Paz, E Donati… - Journal of Colloid and …, 2022 - Elsevier
Hypothesis The positive charge on liposome surface is known to promote the crossing of the
Blood brain barrier (BBB). However, when diastereomeric cationic gemini amphiphiles are …

Lipid-based nanocarriers challenging the ocular biological barriers: Current paradigm and future perspectives

KK Abla, MM Mehanna - Journal of Controlled Release, 2023 - Elsevier
Eye is the most specialized and sensory body organ and treating eye diseases efficiently is
necessary. Despite various attempts, the design of a consummate ophthalmic drug delivery …

SiATG5-loaded cancer cell membrane-fused liposomes induced increased uptake of albumin-bound chemotherapeutics by pancreatic cancer cells

J Yan, M Wang, S Lv, D Chen, Z Wu, D Zhou… - Journal of Controlled …, 2024 - Elsevier
Chemotherapeutic efficacy for pancreatic cancer is severely compromised by limited drug
availability to tumor cells. Herein, we constructed a cancer cell membrane-fused liposome …

[HTML][HTML] A liposomal vaccine promotes strong adaptive immune responses via dendritic cell activation in draining lymph nodes

M Agallou, M Margaroni, E Tsanaktsidou… - Journal of Controlled …, 2023 - Elsevier
Subunit proteins provide a safe source of antigens for vaccine development especially for
intracellular infections which require the induction of strong cellular immune responses …

[HTML][HTML] Meeting contemporary challenges: development of nanomaterials for veterinary medicine

O Danchuk, A Levchenko, R da Silva Mesquita… - Pharmaceutics, 2023 - mdpi.com
In recent decades, nanotechnology has been rapidly advancing in various fields of human
activity, including veterinary medicine. The review presents up-to-date information on recent …

[HTML][HTML] Oral bioavailability enhancement of Vancomycin hydrochloride with cationic nanocarrier (Leciplex): optimization, in vitro, ex vivo, and in vivo studies

MM Abdellatif, SM Ahmed, MA El-Nabarawi… - Scientia …, 2022 - mdpi.com
To explore the performance of the cationic nanocarrier leciplex (LPX) in escalating the oral
bioavailability of vancomycin hydrochloride (VAN) by promoting its intestinal permeability …