Obesity and the metabolic syndrome in developing countries

A Misra, L Khurana - The Journal of Clinical Endocrinology & …, 2008 - academic.oup.com
Context Prevalence of obesity and the metabolic syndrome is rapidly increasing in
developing countries, leading to increased morbidity and mortality due to type 2 diabetes …

Nonalcoholic steatohepatitis: summary of an AASLD Single Topic Conference

BA Neuschwander-Tetri, SH Caldwell - Hepatology, 2003 - Elsevier
Fatty liver disease that develops in the absence of alcohol abuse is recognized increasingly
as a major health burden. This report summarizes the presentations and discussions at a …

Ethnic-specific criteria for classification of body mass index: a perspective for Asian Indians and American Diabetes Association position statement

A Misra - Diabetes technology & therapeutics, 2015 - liebertpub.com
Definitions for overweight and obesity are universally applied using body mass index (BMI),
based on morbidity and mortality data derived from white populations. However, several …

[HTML][HTML] Non-alcoholic fatty liver disease in 2015

M Ahmed - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
There is worldwide epidemic of non-alcoholic fatty liver disease (NAFLD). NAFLD is a
clinical entity related to metabolic syndrome. Majority of the patients are obese but the …

Use of size and a copolymer design feature to improve the biodistribution and the enhanced permeability and retention effect of doxorubicin-loaded mesoporous silica …

H Meng, M Xue, T Xia, Z Ji, DY Tarn, JI Zink, AE Nel - ACS nano, 2011 - ACS Publications
A key challenge for improving the efficacy of passive drug delivery to tumor sites by a
nanocarrier is to limit reticuloendothelial system uptake and to maximize the enhanced …

Lipotoxicity: when tissues overeat

JE Schaffer - Current opinion in lipidology, 2003 - journals.lww.com
Recent studies provide clues regarding the cellular mechanisms that determine whether
excess lipid accumulation is well tolerated or cytotoxic. Critical in this process are …

Obesity and dyslipidemia in South Asians

A Misra, U Shrivastava - Nutrients, 2013 - mdpi.com
Obesity and dyslipidemia are emerging as major public health challenges in South Asian
countries. The prevalence of obesity is more in urban areas than rural, and women are more …

Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects

A Gastaldelli, K Cusi, M Pettiti, J Hardies, Y Miyazaki… - Gastroenterology, 2007 - Elsevier
Background & Aims: Abdominal fat accumulation (visceral/hepatic) has been associated
with hepatic insulin resistance (IR) in obesity and type 2 diabetes (T2DM). We examined the …

[HTML][HTML] Stability of a type 2 diabetes rat model induced by high-fat diet feeding with low-dose streptozotocin injection

X Guo, Y Wang, K Wang, B Ji, F Zhou - Journal of Zhejiang …, 2018 - ncbi.nlm.nih.gov
Objective: The present study aims at determining the stability of a popular type 2 diabetes rat
model induced by a high-fat diet combined with a low-dose streptozotocin injection …

Nonalcoholic steatohepatitis

EM Brunt - Seminars in liver disease, 2004 - thieme-connect.com
BACKGROUND The diagnosis of NAFLD and NASH remains one of clinicopathologic
correlation.[1][2][3] In evaluation of subjects suspected to have NAFLD or NASH, standard …