Methamphetamine use in the United States: epidemiological update and implications for prevention, treatment, and harm reduction

CM Jones, D Houry, B Han, G Baldwin… - Annals of the New …, 2022 - Wiley Online Library
Recent attention has focused on the growing role of psychostimulants, such as
methamphetamine in overdose deaths. Methamphetamine is an addictive and potent …

[HTML][HTML] Drug addiction: from bench to bedside

J Cheron, A Kerchove d'Exaerde - Translational Psychiatry, 2021 - nature.com
Drug addiction is responsible for millions of deaths per year around the world. Still, its
management as a chronic disease is shadowed by misconceptions from the general public …

Substance use disorders: a comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention

ND Volkow, C Blanco - World Psychiatry, 2023 - Wiley Online Library
Substance use disorders (SUDs) are highly prevalent and exact a large toll on individuals'
health, well‐being, and social functioning. Long‐lasting changes in brain networks involved …

[HTML][HTML] Low-intensity focused ultrasound targeting the nucleus accumbens as a potential treatment for substance use disorder: safety and feasibility clinical trial

JJ Mahoney, MW Haut, J Carpenter, M Ranjan… - Frontiers in …, 2023 - frontiersin.org
Introduction While current treatments for substance use disorder (SUD) are beneficial,
success rates remain low and treatment outcomes are complicated by co-occurring SUDs …

[HTML][HTML] Deep brain stimulation in drug addiction treatment: research progress and perspective

R Chang, J Peng, Y Chen, H Liao, S Zhao… - Frontiers in …, 2022 - frontiersin.org
Drug addiction is a chronic psychiatric disorder characterized by compulsive drug-seeking
and drug-using behavior, and a tremendous socioeconomic burden to society. Current …

[HTML][HTML] Targeting opioid receptors in addiction and drug withdrawal: Where are we going?

R Tabanelli, S Brogi, V Calderone - International Journal of Molecular …, 2023 - mdpi.com
This review article offers an outlook on the use of opioids as therapeutics for treating several
diseases, including cancer and non-cancer pain, and focuses the analysis on the …

[HTML][HTML] Drugs, guts, brains, but not rock and roll: The need to consider the role of gut microbiota in contemporary mental health and wellness of emerging adults

JE Lee, D Walton, CP O'Connor, M Wammes… - International Journal of …, 2022 - mdpi.com
Emerging adulthood (ages 18–25) is a critical period for neurobiological development and
the maturation of the hypothalamic–pituitary–adrenal axis. Recent findings also suggest that …

Neuroplasticity, the prefrontal cortex, and psychopathology-related deviations in cognitive control

M Luciana, PF Collins - Annual Review of Clinical Psychology, 2022 - annualreviews.org
A basic survival need is the ability to respond to, and persevere in the midst of, experiential
challenges. Mechanisms of neuroplasticity permit this responsivity via functional adaptations …

[HTML][HTML] Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats

MT Zanda, G Floris, SE Daws - Translational Psychiatry, 2023 - nature.com
Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is
hampered by perseverant drug cravings that may persist for months after cessation of drug …

No time to lose: the current state of research in rapid-acting psychotherapeutics

JA Gordon, ND Volkow, GF Koob - Neuropsychopharmacology, 2024 - nature.com
The vast majority of treatments for psychiatric and substance use disorders take weeks to
work. Notable exceptions to this rule exist, with some treatments such as intravenous …