Patient-specific cardiovascular simulation has become a paradigm in cardiovascular
research and is emerging as a powerful tool in basic, translational and clinical research. In …

Inverse modeling approaches in cardiovascular medicine are a collection of methodologies
that can provide non-invasive patient-specific estimations of tissue properties, mechanical …

Three-D head geometrical models of eight healthy subjects and 11 hydrocephalus patients
were built using their CINE phase-contrast MRI data and used for computer simulations …

Patient-specific simulation plays an important role in cardiovascular disease research,
diagnosis, surgical planning and medical device design, as well as education in …

Blood flow and mechanical forces in the ventricle are implicated in cardiac development and
trabeculation. However, the mechanisms of mechanotransduction remain elusive. This is …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling
resulting in right ventricular (RV) dysfunction and ultimately RV failure. Mechanical stimuli …

Abstract 4D Flow MRI is a diagnostic tool that can visualize and quantify patient-specific
hemodynamics and help interventionalists optimize treatment strategies for repairing …

Hemodynamic shear force has been implicated as modulating Notch signaling–mediated
cardiac trabeculation. Whether the spatiotemporal variations in wall shear stress (WSS) …

We are interested in a reduced order method for the efficient simulation of blood flow in
arteries. The blood dynamics is modeled by means of the incompressible Navier–Stokes …

Biomechanical forces and endothelial-mesenchymal transition (EndoMT) are known to
mediate valvulogenesis. However, the relative contributions of myocardial contractile and …