Nicolau syndrome, although it is quite rare, often occurs following intramuscular injections of
different medications, especially diclofenac and penicillins. Accordingly, its symptoms …

Background Sciatic nerve injury after inadvertent intramuscular gluteal injection is a well-
described entity. We have presented a case of a rare and probably underdiagnosed …

We present a 33‐year‐old female patient with Nicolau syndrome (NS) who received one
injection of benzathine penicillin and one injection of betamethasone to the right buttock …

An intramuscular (IM) injection is one of the common routes for administering drugs,
commonly analgesics and vaccines. Nicolau syndrome refers to the rapid-onset painful …

Methods| We used FDA accelerated approval reports to identify product-indication pairs
granted accelerated approval from January 2009 to December 2019. 1 We reviewed …

Calcium hydroxide has been used successfully in root canal therapy for many years.
However, it can cause serious damage if it is inadvertently displaced into surrounding vital …

Nicolau syndrome (NS) is a rare injection site reaction, following intramuscular injection of
drugs characterized by severe pain, skin discoloration and varying level of tissue necrosis …

Methods| Our evaluation included a case series review, calculation of reporting rate, and a
PubMed search for similar reports. Under statutory authority pursuant to public health, no …

Background: Tissue necrosis is a significant but uncommon complication of sclerotherapy.
The pathogenic mechanisms of this often-debilitating complication have been poorly …

Background Exosomes have gained attention for their potential in skin rejuvenation.
Currently, most exosome products are available for topical administration, and the use of …