Purpose Endometriosis is defined as the presence of endometrial-like endometrial cells,
glands and stroma outside the uterus, causing a strong inflammatory-like microenvironment …

DEAD-box (DDX) 5 and DDX17, which belong to the DEAD-box RNA helicase family, are
nuclear and cytoplasmic shuttle proteins. These proteins are expressed in most tissues and …

G-quadruplexes (G4) are noncanonical secondary structures formed in guanine-rich DNA
and RNA sequences. MYC, one of the most critical oncogenes, forms a DNA G4 in its …

Anti-tumorigenic mechanisms mediated by the tumor suppressor p53, upon oncogenic
stresses, are our bodies' greatest weapons to battle against cancer onset and development …

Purpose: This study was performed to identify the detailed mechanisms by which miR-296-
3p functions as a tumor suppressor to prevent lung adenocarcinoma (LADC) cell growth …

The DEAD-box RNA helicase DDX5 is a member of a family of highly conserved proteins
involved in gene-expression regulation and ATP-dependent RNA helicase activities …

Metabolic reprogramming can contribute to colorectal cancer progression and therapy
resistance. Identification of key regulators of colorectal cancer metabolism could provide …

Background Pancreatic ductal adenocarcinoma (PDAC), a difficult‐to‐treat cancer, is
expected to become the second‐largest cause of cancer‐related deaths by 2030, while …

Various diseases, including cancers, age-associated disorders, and acute liver failure, have
been linked to the oncogene, MYC. Animal testing and clinical trials have shown that …

Many signaling systems execute adaptation under circumstances that require noise
attenuation. Here, we identify an intrinsic trade-off existing between sensitivity and noise …