Cerebral ischemia remains a major cause of morbidity and mortality with little advancement
in subacute treatment options. This review aims to cover and discuss novel insight obtained …

Background and Purpose—Elevated levels of endothelin-1 (ET-1) have been reported in
cerebral ischemia. A role for ET may prove more important if the vascular receptors were …

OBJECTIVE: Inspired by organ culture-induced changes in the vascular endothelin (ET)
receptor population, we investigated whether such changes occur in cerebral arteries in a …

Patients who initially survive the rupture and repair of a brain aneurysm often take a
devastating turn for the worse some days later and die or suffer permanent neurologic …

We have investigated the gene expression in human middle cerebral artery (MCA) after
ischemia. Ischemic stroke affects the perfusion in the affected area and experimental …

Background and Purpose—Previous studies have shown that contractile endothelin type B
(ETB) receptors are upregulated in cerebral arteries after experimental focal cerebral …

To characterize the functional differentiation of neural stem cells into smooth muscle cells,
multipotent stem cells in the central nervous system (CNS) were isolated from rat embryonic …

Subarachnoid hemorrhage (SAH) is associated with increased cerebral artery sensitivity to
vasoconstrictors and release of the perivascular sensory vasodilator CGRP. In the current …

Background Cigarette smoking enhances the risk of stroke. However, the underlying
molecular mechanisms are largely unknown. The present study established an in vivo rat …

The pathogenesis of cerebral ischaemia after subarachnoid haemorrhage (SAH) still
remains elusive. The purpose of the present study was to examine whether specific protein …