TRP (transient receptor potential) ion channel family: Structures, biological functions and therapeutic interventions for diseases
M Zhang, Y Ma, X Ye, N Zhang, L Pan… - Signal Transduction and …, 2023 - nature.com
Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …
[HTML][HTML] Targeting PI3K/AKT signaling pathway in obesity
MS Savova, LV Mihaylova, D Tews, M Wabitsch… - Biomedicine & …, 2023 - Elsevier
Obesity is a disorder with an increasing prevalence, which impairs the life quality of patients
and intensifies societal health care costs. The development of safe and innovative …
and intensifies societal health care costs. The development of safe and innovative …
Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases
S Ji, M Xiong, H Chen, Y Liu, L Zhou, Y Hong… - … and Targeted Therapy, 2023 - nature.com
The ageing process is a systemic decline from cellular dysfunction to organ degeneration,
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells …
Consumption of dietary anthocyanins and their association with a reduction in obesity biomarkers and the prevention of obesity
A Escalante-Aburto, MY Mendoza-Córdova… - Trends in Food Science …, 2023 - Elsevier
Background The emergency for treating obesity has increased, triggering severe economic
issues worldwide. The consumption of anthocyanins from different dietetic sources or by …
issues worldwide. The consumption of anthocyanins from different dietetic sources or by …
[PDF][PDF] The protective roles of citrus flavonoids, naringenin, and naringin on endothelial cell dysfunction in diseases
The endothelial cells (ECs) make up the inner lining of blood vessels, acting as a barrier
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
separating the blood and the tissues in several organs. ECs maintain endothelium integrity …
[HTML][HTML] A narrative review of approved and emerging anti-obesity medications
Background Recently, many drugs have been approved for halting overweight and obesity—
few types of research shifted to using Anti-obesity medications (AOM) solely for well-being …
few types of research shifted to using Anti-obesity medications (AOM) solely for well-being …
Interaction of Jania rubens Polyphenolic Extract as an Antidiabetic Agent with α-Amylase, Lipase, and Trypsin: In Vitro Evaluations and In Silico Studies
Jania rubens red seaweed has various bioactive compounds that can be used for several
medicinal and pharmaceutical applications. In this study, we investigate the antidiabetic, anti …
medicinal and pharmaceutical applications. In this study, we investigate the antidiabetic, anti …
Study of anti-fatigue activity of polysaccharide from fruiting bodies of Armillaria gallica
H Sun, F Shu, Y Guan, F Kong, S Liu, Y Liu… - International journal of …, 2023 - Elsevier
Fatigue is a common physiological response that is closely related to energy metabolism.
Polysaccharides, as excellent dietary supplements, have been proven to have a variety of …
Polysaccharides, as excellent dietary supplements, have been proven to have a variety of …
360-degree perspectives on obesity
M Cuciureanu, CC Caratașu, L Gabrielian… - Medicina, 2023 - mdpi.com
Alarming statistics show that the number of people affected by excessive weight has
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …
surpassed 2 billion, representing approximately 30% of the world's population. The aim of …
An integrative framework to prioritize genes in more than 500 loci associated with body mass index
D Hemerich, V Svenstrup, VD Obrero, M Preuss… - The American Journal of …, 2024 - cell.com
Obesity is a major risk factor for a myriad of diseases, affecting> 600 million people
worldwide. Genome-wide association studies (GWASs) have identified hundreds of genetic …
worldwide. Genome-wide association studies (GWASs) have identified hundreds of genetic …